Association between white opaque substance under magnifying colonoscopy and lipid droplets in colorectal epithelial neoplasms

Figure 6 Endoscopic and histologic features of a lesion with irregular white opaque substance. A: Colonoscopy shows a protruding lesion in the rectum; B: Magnifying endoscopic findings with narrow-band imaging of box in Figure 6a show irregular WOS. WOS is disorganized and asymmetrical; C: Histological examination of the resected specimen shows well to moderately differentiated adenocarcinoma invading the deep submucosal layer (invasion depth; 4,320 μm); D: A low-power view with adipophilin staining shows that the depth of adipophilin expression is deep; E: A high-power view of the box in Figure 6d shows that adipophilin is detected within the neoplastic epithelium. WOS: White opaque substance.