PBX1 attributes as a determinant of connexin 32 downregulation in Helicobacter pylori-related gastric carcinogenesis

Figure 1 Comparison of PBX1 and connexin 32 expression among developmental stages of Helicobacter pylori-associated gastric carcinoma in clinical specimens. Quantitative RT-PCR analysis of PBX1 (A) and Cx32 (B) in H. pylori (-) NGM and H. pylori (+) CAG and GC patients (n = 15). C: Representative images of the PBX1 and Cx32 protein levels in H. pylori (-) NGM and H. pylori (-/+) CAG, IM and GC tissues. ^bP < 0.01, ^eP < 0.001. NGM: Normal gastric mucosa; CAG: Chronic atrophic gastritis; GC: Gastric cancer; IM: Intestinal metaplasia.