Effect of CXCR3/HO-1 genes modified bone marrow mesenchymal stem cells on small bowel transplant rejection

Figure 10 Concentrations of diamine oxidase in different groups. ^aP < 0.05 vs NSBT group ^bP < 0.05 vs IsoT group, ^cP < 0.05 vs NS group, ^dP < 0.05 vs BM group, ^eP < 0.05 vs HB group. The concentration of DAO in the NSBT group was significantly lower than those in the other five groups (P < 0.05). The concentration of DAO in the IsoT group was comparable to that in the HCB group at day 1 (23.43 ± 2.77 M/mL vs 23.26 ± 2.50 M/mL; P < 0.05) and day 3 (24.13 ± 3.51 M/mL vs 23.26 ± 2.50 M/mL; P < 0.05). Serum concentration of DAO in the IsoT group at day 7 (11.14 ± 1.25 M/mL) nearly returned to the level of the NSBT group (10.80 ± 2.78 M/mL). At day 1 after transplantation, serum concentration of DAO in the NS group was significantly higher than those in the BM group, HB group, and HCB group (P < 0.05), comparable in the BM group and HB group (P > 0.05), and was lower in the HCB group when compared with the HB group (P < 0.05). Serum concentration of DAO in the HCB group was significantly lower than those in the NS group, BM group, and HB group at 3 d, 7 d, 10 d, and 14 d (P < 0.05). DAO: Diamine oxidase.