Prognostic implications of FGFR1 and MYC status in esophageal squamous cell carcinoma

Figure 1 Representative images of fluorescence in situ hybridization and immunohistochemistry for fibroblast growth factor receptor 1 and MYC in esophageal squamous cell carcinoma. A and B: High amplification of FGFR1 with increased gene copies of FGFR1 (red signal), compared to chromosome 8 (CEP8, green signal), was observed; C and D: High amplification of MYC with increased gene copies of MYC (orange signal), compared to CEP8 was observed; E and F: MYC immunohistochemistry in the nuclei of tumor cells; E: Weak, F: Strong intensity (original magnification, × 400). FGFR1: Fibroblast growth factor receptor 1.