Clinical analysis of patients with hepatocellular carcinoma recurrence after living-donor liver transplantation

doi:10.3748/wjg.v22.i25.5790

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2016; 22(25): 5790-5799
Published online Jul 7, 2016. doi: 10.3748/wjg.v22.i25.5790

Table 1 Clinicopathological characteristics of patients with hepatocellular carcinoma recurrence after living donor liver transplantation

Factors	Data, n (%)
Recipient age¹	52.0 ± 8.1
Recipient sex, male	46 (85.2)
Etiology
Hepatitis B	46 (85.2)
Hepatitis C	2 (3.7)
Alcohol	5 (9.3)
Other	1 (1.9)
MELD score¹	11.7 ± 8.5
GRWR¹	1.28 ± 0.24
Pre-transplant locoregional treatment	48 (88.9)
Tumor marker at transplantation
AFP¹	717.3 ± 1748.1 (median: 43.3)
HCC characteristics at pathology
Number¹	2.4 ± 1.9 (median: 2.0)
Maximal tumor size (cm)¹	4.85 ± 4.07 (median: 3.8)
Microvascular invasion	30 (60.0)
E-S grade III-IV	25 (52.1)
Beyond Milan criteria	38 (70.4)
Patterns of HCC recurrence
Time between LDLT and recurrence (mo)¹	15.3 ± 23.9 (median: 6.5, range: 1-150)
Single vs multiple	14 (25.9) vs 40 (74.1)
Intrahepatic vs extrahepatic vs both	12 (22.2) vs 37 (68.5) vs 5 (9.3)
Recurrence organ
Lung	24 (44.4)
Liver	17 (31.3)
Bone	10 (18.5)

¹Values are shown as mean ± SD except where stated otherwise. MELD: Model for end-stage liver disease; GRWR: Graft-to-recipient body weight ratio; AFP: Alpha-fetoprotein; HCC: Hepatocellular carcinoma; E-S grade: Edmondson-Steiner grade; LDLT: Living donor liver transplantation.

Citation: Na GH, Hong TH, You YK, Kim DG. Clinical analysis of patients with hepatocellular carcinoma recurrence after living-donor liver transplantation. World J Gastroenterol 2016; 22(25): 5790-5799
URL: https://www.wjgnet.com/1007-9327/full/v22/i25/5790.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i25.5790