Review
Copyright ©The Author(s) 2016.
World J Gastroenterol. Jan 7, 2016; 22(1): 338-348
Published online Jan 7, 2016. doi: 10.3748/wjg.v22.i1.338
Figure 2
Figure 2 Xenobiotic modification of the native lipoyl moiety of the major mitochondrial autoantigen pyruvate dehydrogenase E2, lead to the loss of self-tolerance and eventually biliary lesions in primary biliary cholangitis. PDC-E2: Pyruvate dehydrogenase E2; AMA: Anti-mitochondrial autoantibody.