Characteristic clinical features of Aspergillus appendicitis: Case report and literature review

Figure 2 Photomicrograph. A: Photomicrograph of a hematoxylin-eosin stained, full thickness, cross-section of the resected appendiceal specimen shows a thickened appendiceal wall due to a severe mixed inflammatory infiltrate (A, low power). The high power view (A-inset) of an area within the low-power view, shows one questionable fungal hyphae (arrowhead) within a gland partially destroyed by the necrotizing inflammation; B: Photomicrograph of a Grocott-Gomori methenamine-silver (GMS) nitrate stain reveals invasive, septate, hyphal forms with acutely angled branches, characteristic of Aspergilus species (B-right side-low power, B-left lower inset-high power). The hyphae are confirmed as Aspergillus species by immunohistochemistry (B-left upper inset-high power).