Local corticosterone production and angiotensin-I converting enzyme shedding in a mouse model of intestinal inflammation

Figure 2 Corticosterone production and angiotensin-I converting enzyme shedding measured from healthy (control) and inflamed (DSS 3% or 5% induced in drinking fluid for 7 d) intestine samples (n = 8) after 90 min at 37  °C. All the conditions were pretested in pilot experiments. Corticosterone production measured from the incubate buffer small intestine (A), large intestine (B). ACE shedding into incubate small intestine (C), large intestine (D). Tissue bound ACE from tissue lysate small intestine (E), large intestine (F). Data expressed as mean ± SD, n = 8 in each column. ^aP < 0.05 vs control. ACE: Angiotensin-I converting enzyme; DSS: Dextran sodium sulfate.