Factors predicting aggressiveness of non-hypervascular hepatic nodules detected on hepatobiliary phase of gadolinium ethoxybenzyl diethylene-triamine-pentaacetic-acid magnetic resonance imaging

Figure 2 Representative gadolinium ethoxybenzyl diethylene-triamine-pentaacetic-acid magnetic resonance imaging of non-hypervascular nodules that resolved over time. A: A non-hypervascular nodules (NHNs) was clearly detected at the surface of segment 6 in the hepatobiliary phase, as indicated by an arrowhead in the area ventrolateral to a tiny cyst. The NHN was also revealed in the arterial and equilibrium phases as a lower-intensity nodule, while neither T1-weighted imaging (T1WI) nor T2-weighted imaging visualized the NHN. A fat deposition was expected on the basis of higher intensity in the subtraction of in- and out-of-phase (In-Out) fat-suppressed T1WI. After more than 2 years, the NHN was still there, but the diameter was reduced to less than 5 mm; B: The hepatobiliary phase presented a 6-mm NHN at segment 8 in the vicinity of the diaphragmatic surface of the liver, as indicated by an arrowhead. The NHN could not be visualized in any other sequence. A subsequent gadolinium ethoxybenzyl diethylene-triamine-pentaacetic-acid magnetic resonance imaging showed no nodular lesion in the same area after approximately 5 mo. This NHN was detected together with the other NHN that is presented in Figure 1B.