Pathophysiological roles of Pim-3 kinase in pancreatic cancer development and progression

Figure 1 Amino acid alignment of human Pim family proteins[13]. The amino acid sequences of human Pim family kinases are aligned and common residues shared with Pim-3 are highlighted. The box indicates the hinge region. Residues marked with white and red are important for adenosine triphosphate binding and substrate selectivity, respectively.