Accommodation and peristalsis are functional responses to obstruction in rat hypertrophic ileum

Figure 3 Distension-induced motility. Original tracings representing changes of intraluminal pressure of ileal segments in basal conditions and following application of a hydrostatic pressure of 8 cm H₂O (high distens). A: Normal tissues; B: Control tissues; C: Hypertrophic tissues; D-F: Motor responses in normal (N), control (C) and hypertrophic (H) ileal segments following application of a hydrostatic pressure of 8 cm H₂O (high distens) and incubation with ketanserin 1 μmol/L (K), ondansetron 1 (O1) or 10 (O10) μmol/L or GR125487 1 μmol/L (GR). D: Amplitude (area under the pressure-time curve or AUC); E: Height; F: Frequency. Each value is the mean ± SE of 5 distinct experiments per group. ^bP < 0.001 vs corresponding normal values; ^cP < 0.05, ^dP < 0.001 vs corresponding control values; ^eP < 0.05; ^hP < 0.01. Analysis of variance test followed by Bonferroni’s post-test.