Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure

Figure 3 Comparison of regulatory T cells and T helper 17 cell counts, and the regulatory T cell to T helper 17 cell ratio between acute-on-chronic liver failure survivors and non-survivors, as well as those during the peak of acute-on-chronic liver failure severity (total bilirubin peak) and those during the 8^th week of follow-up. Regulatory T (Treg) cell counts (A), T helper 17 (Th17) cell counts (B), and the Treg cell to Th17 cell ratios (C) of acute-on-chronic liver failure (ACLF) non-survivors, as well as those of ACLF survivors during the total bilirubin (TBIL) peak and during the 8^th week of follow-up. ^aP < 0.05, ^bP < 0.01 vs the 8^th week of follow-up in ACLF survivors, ^dP < 0.01 vs non-survivors. Non-survivors: The non-survivors in ACLF group; Survivors: The survivors in ACLF group during the TBIL peak; Improving: The survivors in ACLF group during the 8^th week of follow-up.