Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure

Figure 1 Percentages of T helper 17 cells and regulatory T cells, and the ratio of regulatory T cells to T helper 17 cells in hepatitis B virus-related acute-on-chronic liver failure, chronic hepatitis B, and normal control groups. Typical four-quadrant graphs of CD25⁺FoxP3⁺ cells [regulatory T (Treg)] and IL17⁺ cells [T helper 17 (Th17)] in CD4⁺ cells were divided into three groups (A). The proportion of Treg cells (B) and Th17 cells (C) among CD4⁺ cells, and the Treg cell to Th17 cell ratios (D) were shown as box plot graphs. Acute-on-chronic liver failure (ACLF) vs chronic hepatitis B group (CHB) ^bP < 0.01; ACLF vs normal control group (NC) ^dP < 0.01; CHB vs NC ^fP < 0.01.