Safety of lamivudine treatment for chronic hepatitis B in early pregnancy

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Dec 7, 2012 (publication date) through Apr 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2012; 18(45): 6645-6650
Published online Dec 7, 2012. doi: 10.3748/wjg.v18.i45.6645

Table 1 Clinical information of mothers who took lamivudine treatment before or during early pregnancy n (%)

	Treated population (n = 92)
Average age (yr)	30.5 ± 3.1
Primipara	88 (95.7)
Cirrhosis	2 (2.2)
HBeAg positivity rate	74 (80.4)
HBV DNA > 10⁵ copies/mL in early pregnancy	16 (17.4)
Treatment before pregnancy
Naive	15 (16.3)
LAM	41 (44.6)
ADV	28 (30.4)
LAM→ADV	3 (3.3)
ETV	2 (2.2)
ETV→ADV	1 (1.1)
IFN + LdT	2 (2.2)

LAM: Lamivudine; ADV: Adefovir dipivoxil; ETV: Entecavir; LdT: Telbivudine; IFN: Interferon; HBeAg: Hepatitis B e antigen.

Citation: Yi W, Liu M, Cai HD. Safety of lamivudine treatment for chronic hepatitis B in early pregnancy. World J Gastroenterol 2012; 18(45): 6645-6650
URL: https://www.wjgnet.com/1007-9327/full/v18/i45/6645.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i45.6645