High dose glargine alters the expression profiles of microRNAs in pancreatic cancer cells

Figure 2 miR-95 promotes cell proliferation (A) and enhancement of miR-95 inhibit apoptosis (B). A total of 10⁴ Sw1990 or Panc-1 cells per well were plated in 96-well plates for 24 h and then were transfected with hsa-miR-95 mimics or hsa-miR-95 inhibitor along with paired negative controls. The cells were incubated at 37 °C for 48 h and then cell proliferation was assessed using Cell Counting Kit 8. Data were shown as mean ± SD. ^aP < 0.05 vs pairing negative control.