HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module

Figure 6 Activation of MLK3-MKK7-JNKs signaling module in hepatitis B virus X protein-transfected HepG2 cells. Transfection of HepG2 cells is described in Figure 2. Forty-eight hours after transfection, the cells lysates were detected by Western blotting analysis. Data are expressed as mean ± SD (n = 3), ^aP < 0.05 vs the HepG2 group; ^cP < 0.05 vs pcDNA3.1-X transfected group and negative control group.