Effects of penehyclidine hydrochloride on rat intestinal barrier function during cardiopulmonary bypass

doi:10.3748/wjg.v17.i16.2137

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2011; 17(16): 2137-2142
Published online Apr 28, 2011. doi: 10.3748/wjg.v17.i16.2137

Table 3 Numbers of animals pretreated with vehicle or penehyclidine hydrochloride with positive bacteriological cultures from blood (portal vein), mesenteric lymph nodes, liver, spleen and lungs after induction of cardiopulmonary bypass

	Portal vein	MLN	Liver	Lungs	Spleen	Total
Controls	0	0	0	0	0	0/40
CPB + vehicle	7	8	6	4	5	30/40^a^c
CPB + L-PHC	3	4	3	2	2	14/30^a^c
CPB + H-PHC	2	3	1	0	0	6/40^a

Controls summarize the results from sham-operated rats treated with saline or penehyclidine hydrochloride (PHC). MLN: Mesenteric lymph node; CPB: Cardiopulmonary bypass; H-PHC: High-dose PHC; L-PHC: Low-dose PHC.

^aP < 0.05 vs controls;

^cP < 0.05 vs L-PHC group.

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Citation: Sun YJ, Cao HJ, Jin Q, Diao YG, Zhang TZ. Effects of penehyclidine hydrochloride on rat intestinal barrier function during cardiopulmonary bypass. World J Gastroenterol 2011; 17(16): 2137-2142
URL: https://www.wjgnet.com/1007-9327/full/v17/i16/2137.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i16.2137

Sun YJ, Cao HJ, Jin Q, Diao YG, Zhang TZ. Effects of penehyclidine hydrochloride on rat intestinal barrier function during cardiopulmonary bypass. World J Gastroenterol 2011; 17(16): 2137-2142 [PMID: 21547135 DOI: 10.3748/wjg.v17.i16.2137]

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