Effects of penehyclidine hydrochloride on rat intestinal barrier function during cardiopulmonary bypass

Table 3 Numbers of animals pretreated with vehicle or penehyclidine hydrochloride with positive bacteriological cultures from blood (portal vein), mesenteric lymph nodes, liver, spleen and lungs after induction of cardiopulmonary bypass

	Portal vein	MLN	Liver	Lungs	Spleen	Total
Controls	0	0	0	0	0	0/40
CPB + vehicle	7	8	6	4	5	30/40ac
CPB + L-PHC	3	4	3	2	2	14/30ac
CPB + H-PHC	2	3	1	0	0	6/40a

Controls summarize the results from sham-operated rats treated with saline or penehyclidine hydrochloride (PHC). MLN: Mesenteric lymph node; CPB: Cardiopulmonary bypass; H-PHC: High-dose PHC; L-PHC: Low-dose PHC.

^aP < 0.05 vs controls;

^cP < 0.05 vs L-PHC group.