Effects of lysophosphatidic acid on human colon cancer cells and its mechanisms of action

Figure 4 LPA stimulated adhesion of SW480 cells. A: Typical image of stained adhered cells (× 200); B: Adhered cells were quantified and relative adhesion rates (mean ± SE) are presented. ^bP < 0.001 vs 0 μmol/L LPA; C: Effect of inhibitors on LPA induced adhesion. 50 μmol/L LPA or LPA plus inhibitors (including 10 μmol/L PD98059, 50 μmol/L LY294002 and 10 μmol/L Y-27632) were added to cells in 96 well plate. Adhered cells were quantified and presented. Results presented as mean ± SE, n = 5. ^bP < 0.001 vs 50 μmol/L LPA.