Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells

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Jan 21, 2009 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 21, 2009; 15(3): 310-320
Published online Jan 21, 2009. doi: 10.3748/wjg.15.310

Table 4 Pathway of down-regulated genes by troglitazone in SNU-668 cells

Term	Count	Pvalue	Genes
DNA Polymerase	8	2.37E-06	PRIM1, RFC5, POLD3, POLE2, POLQ, POLD1, POLE, POLA2
Pyrimidine metabolism	13	6.71E-06	RRM2, TYMS, POLD3, TK1, DTYMK, RRM1, POLR3K, PRIM1, RFC5, POLE2, POLD1, POLE, POLA2
Purine metabolism	14	2.64E-04	RRM2, PAICS, POLD3, PDE7B, RRM1, POLR3K, PRIM1, RFC5, PDE4B, PAPSS2, POLE2, POLD1, POLE, POLA2
Cell cycle	34	3.15E-27	CDK6, BUB1, CDC7, SKP2, PKMYT1, CDC6, MAD2L1, CCNB1, BUB1B, ESPL1, CCNB2, CHEK1, WEE1, MCM5, MCM4, CDKN2C, CDC25A, PCNA, ORC6L, RBL1, ORC1L, MCM2, CDC2, CDK2, MCM6, CDC25C, CCNA2, CDK4, PTTG1, CDC45L, MCM7, PLK1, CDC20, MCM3

Citation: Cheon CW, Kim DH, Kim DH, Cho YH, Kim JH. Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells. World J Gastroenterol 2009; 15(3): 310-320
URL: https://www.wjgnet.com/1007-9327/full/v15/i3/310.htm
DOI: https://dx.doi.org/10.3748/wjg.15.310