Astragalus mongholicus polysaccharide inhibits lipopolysaccharide-induced production of TNF-α and interleukin-8

Figure 3 Astragalus mongholicus polysaccharide inhibits p38 phosphorylation but not ERK1/2 or JNK activation in LPS-stimulated rat small intestinal cells. IEC were treated as described in Figure 1. After incubation in a medium containing 10 &mgr;g/mL LPS with APS at different concentrations of for 1 h, Western blotting analysis was performed to detect phosphorylated p38 (A), total p38 (B), phosphorylated ERK (C), total ERK (D), phosphorylated JNK (E), total JNK (F) and actin (G).