Bone disorders in experimentally induced liver disease in growing rats

Table 1 Serum parameters and body weight in UNT, DP-treated control and DPC-treated rats at wk 8 and 16 (mean±SD)

Parameter	UNT control	UNT control	DP control	DP control	DPC	DPC
	(wk 8)	(wk 16)	(wk 8)	(wk 16)	(wk 8)	(wk 16)
	n = 8	n = 6	n = 10	n = 10	n = 10	n = 11
Bilirubin (mmol/L)	1.8±1.2	2.1±1.3	1.85±0.9	0.88±0.3	48.14±66a	1.31±0.5
ALP (U/L)	735.7±89.3	619.5±96.3	493.9±52.3	402.8±80.2	1 354±1 108a	437.8±116.2
AST (U/L)	112.7±13.3	158.8±40.9	157.3±52.9	127.5±43.3	7 095±5 483a	115.8±15
ALT (U/L)	69.42±8.9	107.8±12.1	158.5±78.4	93.1±71.1	5 175±3 675a	81.54±17.9
Albumin (g/L)	32.85±0.4	34.66±1	33.6±2.2	37.4±1.2	27.8±3a	35.36±1.6
Body weight (g)	240.1±14.3	321.8±48.9	269.4±12.1	307.7±11.3	227.4±16.4	284.2±25.2

^aP<0.05 vs for comparison between DPC and both UNT and DP controls at wk 8.