Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 28, 2024; 30(16): 2184-2190
Published online Apr 28, 2024. doi: 10.3748/wjg.v30.i16.2184
MicroRNAs in inflammatory bowel disease: What do we know and what can we expect?
Ellen Cristina Souza de Oliveira, Ana Elisa Valencise Quaglio, Thais Gagno Grillo, Luiz Claudio Di Stasi, Ligia Yukie Sassaki
Ellen Cristina Souza de Oliveira, Thais Gagno Grillo, Ligia Yukie Sassaki, Department of Internal Medicine, Medical School, São Paulo State University (Unesp), Botucatu 18618-686, São Paulo, Brazil
Ana Elisa Valencise Quaglio, Verum Ingredients, Botucatu Technology Park, Botucatu 18605-525, São Paulo, Brazil
Luiz Claudio Di Stasi, Department of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University (Unesp), Botucatu 18618-689, São Paulo, Brazil
Author contributions: de Oliveira ECS, Quaglio AEV, Grillo TG, Di Stasi LC, and Sassaki LY contributed equally to the conception and design of the article, writing, and editing the manuscript, and review of the literature; All the authors approved the final version of the article to be published.
Supported by Postdoctoral Scholarship Grant, No. 4313/2022 PROPG/PROPE N° 05/2022 from UNESP (to de Oliveira ECS).
Conflict-of-interest statement: The authors report having no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ligia Yukie Sassaki, MD, PhD, Assistant Professor, Department of Internal Medicine, Medical School, São Paulo State University (Unesp), Av Professor Montenegro-Distrito de Rubião Junior, Botucatu 18618-686, São Paulo, Brazil. ligia.sassaki@unesp.br
Received: January 20, 2024
Peer-review started: January 20, 2024
First decision: January 31, 2024
Revised: February 9, 2024
Accepted: March 19, 2024
Article in press: March 19, 2024
Published online: April 28, 2024
Core Tip

Core Tip: MicroRNAs (miRNAs) function in the regulation of inflammatory pathways and the differentiation of intestinal epithelial cells. There is substantial evidence for the important regulatory roles of miRNAs in inflammatory bowel disease (IBD), suggesting that they may serve as biomarkers. Therefore, this editorial aims to present what is already known and what the expectations are regarding the role of miRNAs in IBD.