Rodríguez de Santiago E, Albéniz E, Estremera-Arevalo F, Teruel Sanchez-Vegazo C, Lorenzo-Zúñiga V. Endoscopic anti-reflux therapy for gastroesophageal reflux disease. World J Gastroenterol 2021; 27(39): 6601-6614 [PMID: 34754155 DOI: 10.3748/wjg.v27.i39.6601]
Corresponding Author of This Article
Enrique Rodríguez de Santiago, MD, MHSc, PhD, Consultant Physician-Scientist, Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ctra. de Colmenar Viejo km. 9100, Madrid 28034, Spain. enrodesan@gmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Oct 21, 2021; 27(39): 6601-6614 Published online Oct 21, 2021. doi: 10.3748/wjg.v27.i39.6601
Endoscopic anti-reflux therapy for gastroesophageal reflux disease
Enrique Rodríguez de Santiago, Eduardo Albéniz, Fermin Estremera-Arevalo, Carlos Teruel Sanchez-Vegazo, Vicente Lorenzo-Zúñiga
Enrique Rodríguez de Santiago, Carlos Teruel Sanchez-Vegazo, Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain
Eduardo Albéniz, Fermin Estremera-Arevalo, Endoscopy Unit, Gastroenterology Department, Hospital Universitario de Navarra. Gastrointestinal Endoscopy Research Unit, Navarrabiomed Biomedical Research Center. Pamplona, Spain
Vicente Lorenzo-Zúñiga, Endoscopy Unit, Gastroenterology Department, Hospital Universitari i Politècnic La Fe, Instituto de Investigación Sanitaria La Fe (IIS La Fe), Valencia 46026, Spain
Author contributions: Rodriguez de Santiago E and Lorenzo-Zuñiga V designed the research study; all authors performed the literature review; Rodriguez de Santiago E drafted the first version of the manuscript; Estremera-Arevalo F, Lorenzo-Zuñiga V, Albeniz E, and Teruel Sanchez-Vegazo C critically reviewed the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Enrique Rodríguez de Santiago, MD, MHSc, PhD, Consultant Physician-Scientist, Department of Gastroenterology and Hepatology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ctra. de Colmenar Viejo km. 9100, Madrid 28034, Spain. enrodesan@gmail.com
Received: April 19, 2021 Peer-review started: April 19, 2021 First decision: June 23, 2021 Revised: July 1, 2021 Accepted: August 31, 2021 Article in press: August 31, 2021 Published online: October 21, 2021
Core Tip
Core Tip: Gastroesophageal reflux disease is a common disorder that impacts quality of life. Endoscopic anti-reflux therapies are intended to offer an alternative for patients unwilling to undergo surgical treatment or take lifelong medication. Several techniques, such as transoral incisionless fundoplication, nonablative radiofrequency, plication methods, and anti-reflux mucosectomy, have shown encouraging results, but their role in the management of gastroesophageal reflux disease remains controversial. Careful patient selection and awareness of the advantages and disadvantages of each technique are essential to optimize outcomes. We herein provide an updated review of the technical aspects, clinical success, and safety of the principle endoscopic anti-reflux procedures.
