Mode of delivery by an ulcerative colitis mother in a case of twins: Immunological differences in cord blood and placenta
Garett Dunsmore, Petya Koleva, Reed Taylor Sutton, Lindsy Ambrosio, Vivian Huang, Shokrollah Elahi
Garett Dunsmore, Shokrollah Elahi, Department of Dentistry and Department of Medical Microbiology and Immunology, University of Alberta, Edmonton T6G2E1, Alberta, Canada
Petya Koleva, Department of Dentistry, University of Alberta, Edmonton T6G2E1 Alberta, Canada
Reed Taylor Sutton, Lindsy Ambrosio, Division of Gastroenterology, University of Alberta, Edmonton T6G2E1, Alberta, Canada
Vivian Huang, Division of Gastroenterology, University of Alberta, Edmonton, T6G 2E1, Alberta, Canada and Division of Gastroenterology, University of Toronto, Mount Sinai Hospital, Sinai Health System, Toronto, M5G 1X5, Ontario, Canada
Author contributions: Dunsmore G performed immunology research, analyzed data, wrote the first draft of paper; Koleva P performed PCR research and analyzed data; Sutton TR and Ambrosio L recruited patient and collected clinical data; Huang V designed and performed research; Elahi S conceived and designed research, analyzed data and wrote the manuscript.
Supported by a Foundation Scheme grant and a New Investigator Salary Award from the Canadian Institutes of Health Research (both to Elahi S); and an innovation grant from Women and Children’s Health Research Institute (to Huang V and Elahi S).
Institutional review board statement: This study was reviewed and approved by the review board of the University of Alberta.
Informed consent statement: Informed consent was obtained from the patient.
Conflict-of-interest statement: All authors declare that there are no competing interests.
Data sharing statement: No additional data are available to share.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shokrollah Elahi, MD, PhD, Associate Professor, Department of Dentistry and Department of Medical Microbiology and Immunology, University of Alberta, 7020L, Katz Group Centre for Pharmacology and Health Research, 11361-87th Ave NW, Edmonton T6G2E1, Alberta, Canada. elahi@ualberta.ca
Telephone: +1-780-4921336 Fax: +1-780-4927466
Received: July 23, 2018
Peer-review started: July 23, 2018
First decision: August 25, 2018
Revised: August 29, 2018
Accepted: October 5, 2018
Article in press: October 5, 2018
Published online: November 14, 2018
