Copyright
©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 21, 2017; 23(39): 7168-7173
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7168
Published online Oct 21, 2017. doi: 10.3748/wjg.v23.i39.7168
Expression of annexin A5 in serum and tumor tissue of patients with colon cancer and its clinical significance
Chong-Bing Sun, Ai-Yan Zhao, Xiao-Qing Han, Zuo-Cheng Sun, Meng-Chun Wang, Fu-Chang Zheng, Department of General Surgery, Weifang People’s Hospital, Weifang 261000, Shandong Province, China
Shuai Ji, Department of Anorectal Surgery, Linqu People’s Hospital, Weifang 261000, Shandong Province, China
Author contributions: All authors contributed to the manuscript.
Institutional review board statement: This study is approved by the Local Hospital Review Board.
Informed consent statement: All cases enrolled have signed the consent statement.
Conflict-of-interest statement: No conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Fu-Chang Zheng, Associate Chief Physician, Department of General Surgery, Weifang People's Hospital, 151 Guangwen Road, Weifang 261000, Shandong Province, China. zhengfc@yeah.net
Telephone: +86-536-8192599
Received: February 27, 2017
Peer-review started: February 27, 2017
First decision: April 10, 2017
Revised: June 20, 2017
Accepted: August 8, 2017
Article in press: August 8, 2017
Published online: October 21, 2017
Peer-review started: February 27, 2017
First decision: April 10, 2017
Revised: June 20, 2017
Accepted: August 8, 2017
Article in press: August 8, 2017
Published online: October 21, 2017
Core Tip
Core tip: For patients with colon cancer, annexin A5 expression in cancer tissues is related to lymph node metastasis and tumor grade. Serum level of annexin A5 is related to annexin A5 expression in cancer tissues and is of diagnostic relevance.