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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Apr 28, 2017; 23(16): 2870-2882
Published online Apr 28, 2017. doi: 10.3748/wjg.v23.i16.2870
Published online Apr 28, 2017. doi: 10.3748/wjg.v23.i16.2870
Strategies used by helicobacter pylori to establish persistent infection
Amin Talebi Bezmin Abadi, Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran 14115-111, Iran
Author contributions: Talebi Bezmin Abadi A designed the research, analyzed the data and wrote the article.
Conflict-of-interest statement: Author declares no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Amin Talebi Bezmin Abadi, PhD, Assistant Professor, Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran 14115-111, Iran. amin.talebi@modares.ac.ir
Telephone: +98-21-82884883 Fax: +98-21-82884883
Received: December 5, 2016
Peer-review started: December 6, 2016
First decision: January 10, 2017
Revised: February 1, 2017
Accepted: February 16, 2017
Article in press: February 16, 2017
Published online: April 28, 2017
Peer-review started: December 6, 2016
First decision: January 10, 2017
Revised: February 1, 2017
Accepted: February 16, 2017
Article in press: February 16, 2017
Published online: April 28, 2017
Core Tip
Core tip:Helicobacter pylori (H. pylori) infections are thought to cause severe gastroduodenal disorders which are the main outcome of this interaction between the host and this microorganism. The bacterium has developed interesting strategies which allow it to efficiently colonize the gastric mucosa leading to persistent infection. In this review, we aim to look at the five major reported strategies leading to the persistent survival of H. pylori within gastric epithelial cells.