Retrospective Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Dec 7, 2016; 22(45): 10002-10008
Published online Dec 7, 2016. doi: 10.3748/wjg.v22.i45.10002
Inter- and intraobserver agreement in computed tomography enterography in inflammatory bowel disease
Natally Horvat, Camila Carlos Tavares, Adriana Ribas Andrade, Julia Campos Simões Cabral, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, André Zonetti Arruda Leite, Aytan Miranda Sipahi, Manoel Souza Rocha
Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil
Adriana Ribas Andrade, Julia Campos Simões Cabral, André Zonetti Arruda Leite, Aytan Miranda Sipahi, Gastroenterology Department, Lim 07, Hospital da Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP 05403-000, Brazil
Author contributions: All the authors equally contributed to this paper.
Institutional review board statement: The study was reviewed and approved by the CAPPesq, the Ethics Committee for researches of the institution (CAAE number: 51651915.5.0000.0068).
Informed consent statement: Institutional review board approval was obtained and the requirement for informed written consent was waived.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at natally.rocha@hc.fm.usp.br Participants consent for data sharing was not obtained but the presented data are anonymized and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Natally Horvat, MD, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Rua Dr. Ovídio Pires de Campos, 75, Cerqueira César - São Paulo, SP 05403-010, Brazil. natally.rocha@hc.fm.usp.br
Telephone: +55-11-26617068 Fax: +55-11-26617550
Received: June 18, 2016
Peer-review started: June 20, 2016
First decision: August 22, 2016
Revised: September 8, 2016
Accepted: September 28, 2016
Article in press: September 28, 2016
Published online: December 7, 2016
Core Tip

Core tip: Evaluation of active inflammation in inflammatory bowel disease (IBD) is not simple and demands a multidisciplinary approach. A few studies have evaluated the interobserver agreement in computed tomography enterography (CTE) findings in patients with active inflammation in IBD. Intraobserver agreement was only evaluated in other imaging modalities. This study showed for the first time intraobserver agreement for CTE signs of active IBD and its correlation with fecal calprotectin (FC) levels. We found almost perfect intraobserver and moderate interobserver agreement in the characterization of signs of active disease in CTE, in concurrence with high FC levels in patients with IBD.