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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 14, 2016; 22(34): 7824-7840
Published online Sep 14, 2016. doi: 10.3748/wjg.v22.i34.7824
Published online Sep 14, 2016. doi: 10.3748/wjg.v22.i34.7824
Global epidemiology of hepatitis C virus infection: An up-date of the distribution and circulation of hepatitis C virus genotypes
Arnolfo Petruzziello, Samantha Marigliano, Giovanna Loquercio, Anna Cozzolino, Carmela Cacciapuoti, Laboratory of Virology and Molecular Biology "V.Tridente", IRCCS Italia, Fondazione " G. Pascale", 80131 Naples, Italy
Author contributions: Petruzziello A, Marigliano S, Loquercio G and Cozzolino A acquired the data; Petruzziello A drafted the article and contributed to conception and design; Cacciapuoti C contributed to critical revision for important intellectual content; all authors approved the final version to be published.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Data sharing statement: Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Arnolfo Petruzziello, PhD, Laboratory of Virology and Molecular Biology "V. Tridente", IRCCS Italia, Fondazione " G. Pascale", Via Mariano Semmola, 80131 Naples, Italy. a.petruzziello@istitutotumori.na.it
Telephone: +39-81-5903433 Fax: +39-81-5453854
Received: April 15, 2016
Peer-review started: April 18, 2016
First decision: May 12, 2016
Revised: June 28, 2016
Accepted: August 8, 2016
Article in press: August 8, 2016
Published online: September 14, 2016
Peer-review started: April 18, 2016
First decision: May 12, 2016
Revised: June 28, 2016
Accepted: August 8, 2016
Article in press: August 8, 2016
Published online: September 14, 2016
Core Tip
Core tip: Hepatitis C virus (HCV) infection is a global public health burden, causing an increasing level of liver-related morbidity and mortality due to the disease progression. Unfortunately, in many countries, there is a lack of robust epidemiological data, especially HCV genotypes distribution, upon which to base country-specific prevention, diagnosis and treatment strategies in order to reduce the disease burden represented by HCV. Stratification by viral genotypes at national and regional level, and a better understanding of viral diversity within target populations, might also critically inform the rational design and testing of future HCV vaccines.