Friedel D, Modayil R, Stavropoulos SN. Per-oral endoscopic myotomy: Major advance in achalasia treatment and in endoscopic surgery. World J Gastroenterol 2014; 20(47): 17746-17755 [PMID: 25548473 DOI: 10.3748/wjg.v20.i47.17746]
Corresponding Author of This Article
Stavros N Stavropoulos, MD, Director of Endoscopy, Department of Gastroenterology, Hepatology and Nutrition, Winthrop University Hospital, 222 Station Plaza North Suite 429, Mineola, NY 11501, United States. sstavropoulos@winthrop.org
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Topic Highlight
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World J Gastroenterol. Dec 21, 2014; 20(47): 17746-17755 Published online Dec 21, 2014. doi: 10.3748/wjg.v20.i47.17746
Per-oral endoscopic myotomy: Major advance in achalasia treatment and in endoscopic surgery
David Friedel, Rani Modayil, Stavros N Stavropoulos
David Friedel, Rani Modayil, Stavros N Stavropoulos, Department of Gastroenterology, Hepatology and Nutrition, Winthrop University Hospital, Mineola, NY 11501, United States
Author contributions: Friedel D contributed to the manuscript preparation; Modayil R contributed to the manuscript, tables and figures preparation; Stavropoulos SN contributed to the manuscript preparation, informational source and final approval of version published.
Correspondence to: Stavros N Stavropoulos, MD, Director of Endoscopy, Department of Gastroenterology, Hepatology and Nutrition, Winthrop University Hospital, 222 Station Plaza North Suite 429, Mineola, NY 11501, United States. sstavropoulos@winthrop.org
Telephone: +1-516-6634623 Fax: +1-516-6634617
Received: June 13, 2014 Revised: July 20, 2014 Accepted: November 30, 2014 Published online: December 21, 2014
Core Tip
Core tip: Per-oral endoscopic myotomy (POEM) is a novel endosurgical therapy for achalasia. POEM developed as an offshoot of early natural orifice endoscopic surgery (NOTES) approach investigation, but, now, is arguably the most successful clinical application of NOTES. The clinical results of POEM therapy in terms of dysphagia relief and safety have been excellent. The impact of POEM is extending far beyond the narrow domain of esophageal motility disorders. As the first successful clinical application of submucosal endoscopy it is now spawning many other NOTES interventions utilizing a submucosal tunnel approach including submucosal tunnel endoscopic resection of submucosal and mucosal lesions and per oral pyloromyotomy for gastroparesis.
