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World J Gastroenterol. Oct 28, 2014; 20(40): 14559-14567
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14559
Hepatitis B virus and hepatitis C virus dual infection
Gaia Caccamo, Francesca Saffioti, Giovanni Raimondo
Gaia Caccamo, Francesca Saffioti, Giovanni Raimondo, Division of Clinical and Molecular Hepatology, Department of Internal Medicine, University Hospital of Messina, 98124 Messina, Italy
Author contributions: Caccamo G and Raimondo G wrote and revised the paper; Saffioti F contributed to the bibliographic research and revised the paper.
Correspondence to: Giovanni Raimondo, MD, Professor, Chief, Division of Clinical and Molecular Hepatology, Department of Internal Medicine, University Hospital of Messina, Via Consolare Valeria 1, 98124 Messina, Italy. raimondo@unime.it
Telephone: +39-90-2212392 Fax: +39-90-2213594
Received: October 29, 2013
Revised: March 24, 2014
Accepted: May 19, 2014
Published online: October 28, 2014
Core Tip

Core tip: This review analyses the available virological and clinical data about the dual hepatitis B virus/hepatitis C virus infection. In particular, it highlights the aspects concerning the possible viral interactions, the impact on liver disease progression and hepatocellular carcinoma development as well as the therapeutic options in this special population.