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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 7, 2014; 20(33): 11878-11885
Published online Sep 7, 2014. doi: 10.3748/wjg.v20.i33.11878
Published online Sep 7, 2014. doi: 10.3748/wjg.v20.i33.11878
Influence of a probiotic mixture on antibiotic induced microbiota disturbances
Sofia Forssten, Arthur C Ouwehand, Active Nutrition, DuPont Nutrition & Health, 02460 Kantvik, Finland
Malkanthi Evans, Dale Wilson, KGK Synergize, London, ON N6A 5R8, Canada
Author contributions: All authors contributed to the writing of the manuscript and interpretation of the data; Wilson D and Ouwehand AC designed the study; Forssten S performed the microbiota and antibiotic resistance analyses; Evans M performed the statistical analyses; Wilson D performed the study.
Supported by The study was commissioned and paid for by DuPont Nutrition & Health
Correspondence to: Arthur C Ouwehand, PhD, Research Manager, Active Nutrition, DuPont Nutrition & Health, Sokeritehtaantie 20, 02460 Kantvik, Finland. arthur.ouwehand@dupont.com
Telephone: +358-40-5956353 Fax: +358-10-4315601
Received: December 29, 2013
Revised: March 13, 2014
Accepted: May 12, 2014
Published online: September 7, 2014
Revised: March 13, 2014
Accepted: May 12, 2014
Published online: September 7, 2014
Core Tip
Core tip: The influence of a probiotic combination on the stability of the intestinal microbiota was studied using molecular techniques. Most published studies have relied on culturing or have only looked at symptomology. Furthermore, this was studied in a antibiotic challenge setting to limit variability.