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World J Gastroenterol. Jan 21, 2014; 20(3): 745-754
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.745
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.745
Transarterial chemoembolization in Barcelona Clinic Liver Cancer Stage 0/A hepatocellular carcinoma
Heung Cheol Kim, Department of Radiology, Hallym University College of Medicine, Chuncheon 200-704, South Korea
Ki Tae Suk, Dong Joon Kim, Jai Hoon Yoon, Yeon Soo Kim, Gwang Ho Baik, Jin Bong Kim, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon 200-704, South Korea
Chang Hoon Kim, College of Medicine, Upstate Medical University, State University of New York, Syracuse, NY 13210, United States
Hotaik Sung, Department of Biology, Stanford University, Stanford, CA 94305, United States
Jong Young Choi, Department of Internal Medicine, Catholic University College of Medicine, Seoul 137-701, South Korea
Kwang Hyub Han, Liver Cirrhosis Clinical Research Center, Yonsei University College of Medicine, Seoul 542-804, South Korea
Seung Ha Park, Department of Internal Medicine, Inje University College of Medicine, Busan 614-735, South Korea
Author contributions: Kim HC and Suk KT designed the study and wrote the manuscript; Kim HC and Suk KT contributed equally to this work; Kim DJ designed and performed the study and edited the manuscript; Choi JY and Han KH provided vital reagents and analytical tools, were involved in editing the manuscript, and provided financial support for this work; Yoon JH, Kim YS, Baik GH and Kim JB coordinated and collected all of the human data; Kim CH, Sung H and Park SH were involved in editing the manuscript.
Supported by A Grant from the Korea Healthcare Technology R and D Project, Ministry of Health and Welfare, Republic of Korea No. HI10C2020); by The Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology No. NRF-2010-0021482
Correspondence to: Dong Joon Kim, MD, PhD, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon 200-704, South Korea. djkim@hallym.ac.kr
Telephone: +82-33-2405647 Fax: +82-33-2418064
Received: July 22, 2013
Revised: October 17, 2013
Accepted: October 19, 2013
Published online: January 21, 2014
Revised: October 17, 2013
Accepted: October 19, 2013
Published online: January 21, 2014
Core Tip
Core tip: In this study, transarterial chemoembolization (TACE) was associated with a relatively good survival rate in patients with stage 0 and stage A Barcelona Clinic Liver Cancer (BCLC). The Child-Pugh score, presence of arterio-venous shunt, amount of lipiodol used during TACE, and female gender were correlated with mortality in patients with BCLC stage 0 and stage A hepatocellular carcinoma who underwent TACE. Patients with more than 2 risk factors should be treated by other curative-intent treatments after the first TACE.