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World J Gastroenterol. Jul 28, 2014; 20(28): 9338-9344
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9338
Role of diet and lifestyle changes in nonalcoholic fatty liver disease
William Nseir, Elias Hellou, Nimer Assy
William Nseir, Elias Hellou, Department of Internal Medicine, EMMS, The Nazareth Hospital, Nazareth 16100, Israel
William Nseir, Nimer Assy, Faculty of Medicine in the Galilee, Bar-Ilan University, Safed 13100, Israel
Nimer Assy, Liver Unit, Ziv Medical Center, Safed 13100, Israel
Author contributions: Nseir W wrote the manuscript and participated in the design, editing, and polishing; Hellou E participated in the design; Assy N participated in the design, editing, and polishing.
Correspondence to: William Nseir, MD, Department of Internal Medicine, EMMS, The Nazareth Hospital, POBox 11, Nazareth 16100, Israel. w.nseir@yahoo.com
Telephone: +972-4-6028851  Fax: +972-4-6028851
Received: November 4, 2013
Revised: February 24, 2014
Accepted: April 15, 2014
Published online: July 28, 2014
Core Tip

Core tip: To date there is no effective drug treatment for nonalcoholic fatty liver disease (NAFLD). A combination of dietary modifications and increased physical activity remains the mainstay of NAFLD therapy. In order to prevent the hepatic, extra-hepatic, including metabolic complications of NAFLD, it is important to manage this condition early. Therefore, a plan should be carried out immediately when NAFLD is diagnosed combining diet and proper exercise activity. This review highlights the role of diet and lifestyle changes in the management of NAFLD, and focuses on human studies regarding dietary modifications and physical activity.