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World J Gastroenterol. Jul 28, 2014; 20(28): 9270-9280
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9270
Epidemiology and natural history of hepatitis C virus infection
Mei-Hsuan Lee, Hwai-I Yang, Yong Yuan, Gilbert L’Italien, Chien-Jen Chen
Mei-Hsuan Lee, the Institute of Clinical Medicine, National Yang-Ming University, Taipei 155, Taiwan
Hwai-I Yang, Chien-Jen Chen, the Genomics Research Center, Academia Sinica, Taipei 115, Taiwan
Hwai-I Yang, the Graduate Institute of Clinical Medical Science, China Medical University, Taichung 40242, Taiwan
Hwai-I Yang, the Molecular and Genomic Epidemiology Center, China Medical University Hospital, Taichung 40242, Taiwan
Yong Yuan, Gilbert L’Italien, the Global Health Economics and Outcomes Research, Bristol-Myers Squibb, Princeton, NJ 08543, United States
Gilbert L’Italien, the Yale University School of Medicine, New Haven, CT 06510, United States
Chien-Jen Chen, the Graduate Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 155, Taiwan
Author contributions: Lee MH generated the figures and wrote the manuscript; Lee MH, Yang HI, Yuan Y, L’Italien G and Chen CJ contributed to the writing of the manuscript.
Correspondence to: Chien-Jen Chen, ScD, Professor, the Genomics Research Center, Academia Sinica, 128 Academia Road, Section 2, Nankang, Taipei 115, Taiwan. chencj@gate.sinica.edu.tw
Telephone: + 886-2-27899402 Fax: + 886-2-27853208
Received: September 23, 2013
Revised: March 4, 2014
Accepted: April 27, 2014
Published online: July 28, 2014
Core Tip

Core tip: This review includes summary tables describing the epidemiology of hepatitis C virus (HCV) infection in previous studies and recent findings from the risk evaluation of viral load elevation and associated liver disease/cancer in HCV study.