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World J Gastroenterol. Jul 14, 2014; 20(26): 8377-8392
Published online Jul 14, 2014. doi: 10.3748/wjg.v20.i26.8377
Non-alcoholic fatty liver disease and diabetes: From physiopathological interplay to diagnosis and treatment
Nathalie C Leite, Cristiane A Villela-Nogueira, Claudia R L Cardoso, Gil F Salles
Nathalie C Leite, Cristiane A Villela-Nogueira, Claudia R L Cardoso, Gil F Salles, Internal Medicine Department, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Rio de Janeiro 22750-240, Brazil
Author contributions: Leite NC and Villela-Nogueira CA contributed equally to this work, both reviewed the subject and drafted the manuscript; Cardoso CRL and Salles GF reviewed the manuscript and contributed with intellectual content.
Supported by Conselho Brasileiro de Desenvolvimento Científico e Tecnológico (CNPq-Brasil) and Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ-Brasil)
Correspondence to: Gil F Salles, MD, PhD, Professor, Internal Medicine Department, University Hospital Clementino Fraga Filho, School of Medicine, Universidade Federal do Rio de Janeiro, Rua Croton 72, Rio de Janeiro 22750-240, Brazil. gilsalles@hucff.ufrj.br
Telephone: +55-21-24473577 Fax: +55-21-25622514
Received: October 26, 2013
Revised: December 1, 2013
Accepted: January 19, 2014
Published online: July 14, 2014
Core Tip

Core tip: This review addresses the important interplay between non-alcoholic fatty liver disease and diabetes mellitus, with particular emphasis on physiopathological mechanisms, diagnosis and treatment.