Meta-Analysis
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World J Gastroenterol. Jun 14, 2014; 20(22): 7034-7039
Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7034
Does hyoscine butylbromide really improve polyp detection during colonoscopy? A meta-analysis of randomized controlled trials
Pei-Jing Cui, Jing Yao, Hua-Zhong Han, Yi-Jun Zhao, Jun Yang
Pei-Jing Cui, Department of Geriatrics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Jing Yao, Hua-Zhong Han, Yi-Jun Zhao, Jun Yang, Department of Surgery, Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Author contributions: Cui PJ and Yao J contributed equally to this work; Yang J designed the research; Cui PJ, Yao J and Zhao YJ performed the data search and meta-analysis; Han HZ and Yang J wrote the paper.
Correspondence to: Jun Yang, MD, PhD, Department of Surgery, Sixth People’s Hospital, Shanghai Jiao Tong University, Xuhui District, No. 600 Yishan Road, Shanghai 200233, China. yangjuns@foxmail.com
Telephone: +86-21-64369181 Fax: +86-21-64368920
Received: November 12, 2013
Revised: January 12, 2014
Accepted: February 20, 2014
Published online: June 14, 2014
Core Tip

Core tip: There is a debate as to whether hyoscine butylbromide can really improve polyp detection during colonoscopy. We performed a meta-analysis of the results of randomized controlled trials to investigate the benefits of hyoscine butylbromide in polyp detection during colonoscopy. We found that the use of hyoscine butylbromide did not significantly improve the polyp detection rate during colonoscopy.