Review
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World J Gastroenterol. Jan 7, 2014; 20(1): 126-132
Published online Jan 7, 2014. doi: 10.3748/wjg.v20.i1.126
Role of BMSCs in liver regeneration and metastasis after hepatectomy
Hua-Lian Hang, Qiang Xia
Hua-Lian Hang, Qiang Xia, Department of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
Author contributions: Hang HL designed the study and wrote the manuscript; Xia Q coordinated and provided the collection of all the human material, in addition to providing financial support for this work.
Supported by The National Natural Science Foundation of China, No. 81100306; and the Science and Technology Commission Medical Foundation of Shanghai, No. 134119a9501
Correspondence to: Qiang Xia, Professor, Department of Liver Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiaotong University, No. 1630 Dongfang Road Pudong New Area, Shanghai 200127, China. xiaqiang@medmail.com.cn
Telephone: +86-21-68383775 Fax: +86-21-58737232
Received: July 21, 2013
Revised: November 13, 2013
Accepted: November 28, 2013
Published online: January 7, 2014
Core Tip

Core tip: Recent research has demonstrated that bone-marrow stromal cells (BMSCs) are a type of stem cell with powerful proliferative and differential potential that play an important role in the repair and regeneration of multiple organs and tissues, and these cells have become the focus of recent research. This review discusses the involvement of BMSCs in liver regeneration and metastasis after hepatectomy.