Meta-Analysis
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World J Gastroenterol. Oct 28, 2013; 19(40): 6919-6927
Published online Oct 28, 2013. doi: 10.3748/wjg.v19.i40.6919
Restrictive vs liberal transfusion for upper gastrointestinal bleeding: A meta-analysis of randomized controlled trials
Juan Wang, Yong-Xin Bao, Ming Bai, Yong-Guo Zhang, Wen-Da Xu, Xing-Shun Qi
Juan Wang, Xing-Shun Qi, Department of Gastroenterology, No. 463 Hospital of Chinese PLA, Shenyang 110042, Liaoning Province, China
Yong-Xin Bao, Post-doctoral Research Station, Shenyang General Hospital of Chinese PLA, Shenyang 110016, Liaoning Province, China
Ming Bai, Xing-Shun Qi, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Yong-Guo Zhang, Wen-Da Xu, Department of Gastroenterology, Shenyang General Hospital of Chinese PLA, Shenyang 110016, Liaoning Province, China
Author contributions: Qi XS is the guarantor of the study; Wang J and Qi XS designed the study and performed literature retrieval and data collection; Wang J, Bao YX, Bai M, Zhang YG, Xu WD and Qi XS analyzed the data and interpreted the results; Wang J and Qi XS drafted the paper; Wang J, Bao YX, Bai M, Zhang YG, Xu WD and Qi XS revised the paper.
Correspondence to: Xing-Shun Qi, MD, Department of Gastroenterology, No. 463 Hospital of Chinese PLA, Dadong Xiaohe Yan Road 46, Shenyang 110042, China. xingshunqi@126.com
Telephone: +86-24-28845200 Fax: +86-24-24835206
Received: July 9, 2013
Revised: August 16, 2013
Accepted: September 4, 2013
Published online: October 28, 2013
Core Tip

Core tip: Current international consensus recommends restrictive transfusion for upper gastrointestinal bleeding. However, this recommendation is largely based on expert opinions. We have performed the present meta-analysis of randomized controlled trials, which potentially supported the superiority of restrictive over liberal transfusion for upper gastrointestinal bleeding.