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World J Gastroenterol. Oct 14, 2013; 19(38): 6408-6415
Published online Oct 14, 2013. doi: 10.3748/wjg.v19.i38.6408
Published online Oct 14, 2013. doi: 10.3748/wjg.v19.i38.6408
Irritable bowel syndrome and organic diseases: A comparative analysis of esophageal motility
Thomas Thomaidis, Markus Moehler, Peter Robert Galle, Andreas Schwarting, Medical Clinic, Johannes-Gutenberg University, 55131 Mainz, Rheinland-Pfalz, Germany
Martin Goetz, Medical Clinic, University of Tuebingen, 72076 Tuebingen, Baden-Württemberg, Germany
Sebastian Paul Gregor, Medical Clinic, SHG-Hospital, 55743 Idar-Oberstein, Rheinland-Pfalz, Germany
Arthur Hoffman, Ralf Kiesslich, Medical Clinic, 60318 Frankfurt am Main, Hessen, Germany
Elias Kouroumalis, Clinic of Gastroenterology, Medical School of Crete, 71110 Heraklion, Crete, Greece
Andreas Schwarting, Sana Rheumatology Centre, 55543 Bad Kreuznach, Rheinland-Pfalz, Germany
Author contributions: Thomaidis T, Kouroumalis E and Kiesslich R designed the research; Thomaidis T, Goetz M and Gregor SP performed the research; Galle PR, Schwarting A and Moehler M contributed to the recruitment of patients; Thomaidis T and Kiesslich R analyzed the data; Thomaidis T, Hoffman A and Kiesslich R wrote the paper.
Correspondence to: Thomas Thomaidis, MD, Medical Clinic, Johannes-Gutenberg University, Saarstraße 21, 55131 Mainz, Rheinland-Pfalz, Germany. thomas.thomaidis@unimedizin-mainz.de
Telephone: +49-6131-177146 Fax: +49-6131-173438
Received: December 14, 2012
Revised: March 26, 2013
Accepted: May 9, 2013
Published online: October 14, 2013
Revised: March 26, 2013
Accepted: May 9, 2013
Published online: October 14, 2013
Core Tip
Core tip: This is the first comparative study concerning esophageal motility among functional and autoimmune disorders. Patients in irritable bowel syndrome (IBS)-group showed comparable dysphagia-scores as patients with systemic lupus erythematosus and systemic sclerosis. Nevertheless, different manometric patterns between the three examined groups were observed, which might allow differentiating esophageal symptoms based on IBS from other organic diseases.