Case Report
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 14, 2015; 21(10): 3150-3153
Published online Mar 14, 2015. doi: 10.3748/wjg.v21.i10.3150
Adenomas of the common bile duct in familial adenomatous polyposis
Mao-Lin Yan, Jun-Yong Pan, Yan-Nan Bai, Zhi-De Lai, Zhong Chen, Yao-Dong Wang
Mao-Lin Yan, Jun-Yong Pan, Yan-Nan Bai, Zhi-De Lai, Zhong Chen, Yao-Dong Wang, Department of Hepatobiliary Surgery, Fujian Provincial Hospital, The Shengli Clinical Medical College of Fujian Medical University, Fuzhou 350001, Fujian Province, China
Author contributions: Yan ML and Wang YD contributed equally to this work; Yan ML, Wang YD, Lai ZD and Pan JY performed the surgery and clinical care of the patient; Yan ML, Pan JY, Bai YN and Chen Z organized the patient’s data and figures; Yan ML and Pan JY wrote the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Yao-Dong Wang, MD, Department of Hepatobiliary Surgery, Fujian Provincial Hospital, The Shengli Clinical Medical College of Fujian Medical University, Dongjie Road 134, Fuzhou 350001, Fujian Province, China. wangyaodongch@163.com
Telephone: +86-591-88127140 Fax: +86-591-87557768
Received: July 19, 2014
Peer-review started: July 20, 2014
First decision: August 15, 2014
Revised: September 14, 2014
Accepted: October 14, 2014
Article in press: October 15, 2014
Published online: March 14, 2015
Abstract

Familial adenomatous polyposis (FAP) or Gardner’s syndrome is often accompanied by adenomas of the stomach and duodenum. We experienced a case of adenomas of the common bile duct in a 40-year-old woman with FAP presenting with acute cholangitis. Only 8 cases of adenomas or adenocarcinoma of the common bile duct have been reported in the literature in patients with FAP or Gardner’s syndrome. Those patients presented with acute cholangitis or pancreatitis. Local excision or Whipple procedure may be the reasonable surgical option.

Keywords: Acute cholangitis, Gardner’s syndrome, Familial adenomatous polyposis, Common bile duct

Core tip: Adenomas or adenocarcinoma in familial adenomatous polyposis (FAP) and Gardner’s syndrome are less frequently in the common bile duct (CBD). We report a case of FAP associated with CBD adenomas presenting with symptoms of acute cholangitis and cured after a radical Whipple procedure.