Case Report
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World J Gastroenterol. Sep 7, 2013; 19(33): 5581-5585
Published online Sep 7, 2013. doi: 10.3748/wjg.v19.i33.5581
Selective endoscopic ligation for treatment of upper gastrointestinal protuberant lesions
Lin Wang, Shi-Yao Chen, Ying Huang, Jie Wu, Ying-Kit Leung
Lin Wang, Shi-Yao Chen, Ying Huang, Jie Wu, Ying-Kit Leung, Department of Gastroenterology, Children’s Hospital of Fudan University, Shanghai 201102, China
Shi-Yao Chen, Department of Gastroenterology, Zhongshan Hospital of Fudan University, Shanghai 200032, China
Author contributions: Chen SY, Huang Y and Wu J designed the study and performed the technique; Wang L and Huang Y wrote the paper; Huang Y and Leung YK were involved in modifying the language.
Supported by The 2011 Ministry of Health Key Clinical Speciality Center Project, China
Correspondence to: Ying Huang, MD, PhD, Department of Gastroenterology, Children’s Hospital of Fudan University, No. 399 Wan-Yuan Road, Shanghai 201102, China. yhuang815@163.com
Telephone: +86-21-64931727 Fax: +86-21-64931901
Received: May 23, 2013
Revised: July 10, 2013
Accepted: July 17, 2013
Published online: September 7, 2013
Abstract

This study explored the clinical value of endoscopic ligation for the treatment of upper gastrointestinal (GI) protuberant lesions in children. According to the appearance and size of lesions, we used different ligation techniques for the treatment of the lesions. Endoscopic ultrasonography was used for preliminary characterization of the lesions. One case diagnosed with Peutz-Jeghers syndrome was successfully treated by a detachable snare. Two cases with semi-pedunculated or broad-base lesions originating from the submucosal layer of the upper GI were treated with endoscopic variceal ligation; endoscopic examination showed that one case had complete healing 11 wk after ligation, while an ulcer scar was observed at the ligation site after 6 wk in the other case. All lesions were successfully ligated at the first attempt. No significant complications occurred either during or after the procedure. Selective endoscopic ligation of upper GI lesions is an effective and safe treatment for upper GI protuberant lesions in children.

Keywords: Endoscopy, Ligation, Endoscopic ultrasonography, Protuberant lesion, Children

Core tip: Endoscopic ligation is an effective method in the management of protuberant lesions. It is less invasive and less expensive than surgical interventions. However, there are few studies of this technique in the treatment of upper gastrointestinal (GI) lesions in children. This paper reports selective endoscopic ligation for the treatment of different upper GI protuberant lesions in children. Endoscopic ultrasonography was used to determine the depth of invasion and provided a preliminary characterization of the lesions.