Case Report
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World J Gastroenterol. Jun 21, 2013; 19(23): 3703-3706
Published online Jun 21, 2013. doi: 10.3748/wjg.v19.i23.3703
Gastric body diaphragm-like stricture as a rare complication of nonsteroidal anti-inflammatory drugs
Li-Li Wu, Yun-Sheng Yang, Feng-Chun Cai, Shu-Fang Wang
Li-Li Wu, Yun-Sheng Yang, Feng-Chun Cai, Shu-Fang Wang, Department of Gastroenterology and Hepatology, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
Author contributions: Wu LL and Yang YS contributed substantially to the conception and design of the data, drafted the paper and approved the version to be published; Cai FC and Wang SF contributed substantially to analysis and interpretation of the data and approved the version to be published.
Correspondence to: Yun-Sheng Yang, MD, PhD, Department of Gastroenterology and Hepatology, Chinese People’s Liberation Army General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China. sunny888@medmail.com.cn
Telephone: +86-10-55499007 Fax: +86-10-55499007
Received: December 18, 2012
Revised: February 27, 2013
Accepted: April 3, 2013
Published online: June 21, 2013
Abstract

Increased risk due to nonsteroidal anti-inflammatory drugs (NSAIDs) therapy has been observed in patients. Although diaphragm-like stricture in the small bowel and colon induced by NSAIDs therapy has been rarely reported, gastric body diaphragm-like stricture has not been reported. We describe the first case of gastric body diaphragm-like stricture due to NSAIDs in a 44-year-old male patient who was successfully treated by an endoscopic approach to avoid complicated surgery. This case highlights new insight into the disadvantages of NSAIDs and provides new data for future clinical studies.

Keywords: Gastric, Gastroscopy, Diaphragm, Stricture, Nonsteroidal anti-inflammatory drug

Core tip: The major disadvantage of nonsteroidal anti-inflammatory drugs (NSAIDs) therapy is the potential to induce adverse gastrointestinal effects. However, diaphragm disease is a rare complication of long-term NSAIDs use. In this study, the first case of NSAIDs-induced diaphragm-like stricture in the gastric body is reported which was successfully treated by an endoscopic approach to avoid a complicated surgical intervention.