Case Reports
Copyright ©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 1, 2004; 10(17): 2616-2617
Published online Sep 1, 2004. doi: 10.3748/wjg.v10.i17.2616
Brunner's gland adenoma of duodenum: A case report and literature review
Yu-Ping Gao, Jian-Shan Zhu, Wen-Jun Zheng
Yu-Ping Gao, Jian-Shan Zhu, Wen-Jun Zheng, Department of Pathology, Affiliated Renji Hospital, Shanghai Second Medical University, Shanghai 200001, China
Author contributions: All authors contributed equally to the work.
Correspondence to: Dr Yu-Ping Gao, Department of Pathology, Affiliated Renji Hospital, Shanghai Second Medical University, 145 Shandong (c) Road, Shanghai 200001, China. jzmgyp@online.sh.cn
Telephone: +86-21-58752345 Ext. 3349 Fax: +86-21-58752345 Ext. 3349
Received: November 21, 2003
Revised: January 4, 2004
Accepted: January 15, 2004
Published online: September 1, 2004
Abstract

AIM: To analyze the clinicopathological features of Brunner's gland adenoma of the duodenum.

METHODS: A rare case of Brunner's gland adenoma of the duodenum was described and related literature was reviewed.

RESULTS: Brunner's gland adenoma of the duodenum appeared to be nodular hyperplasia of the normal Brunner's gland with an unusual admixture of normal tissues, including ducts, adipose tissue and lymphoid tissue. We suggested that it might be designated as a duodenal hamartoma rather than a true neoplasm.

CONCLUSION: The most common location of the lesion is the posterior wall of the duodenum near the junction of its first and second portions. It can result in gastrointestinal hemorrhage and duodenal obstruction. Endoscopic polypectomy is a worthy treatment for benign Brunner's gland adenomas, as malignant changes in these tumors have never been proven.

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