BPG is committed to discovery and dissemination of knowledge
Cited by in CrossRef
For: Gupta MK, Qin RY. Mechanism and its regulation of tumor-induced angiogenesis. World J Gastroenterol 2003; 9(6): 1144-1155 [PMID: 12800214 DOI: 10.3748/wjg.v9.i6.1144]
URL: https://www.wjgnet.com/1007-9327/full/v9/i6/1144.htm
Number Citing Articles
1
Marzena Łazarczyk, Michel Edwar Mickael, Dominik Skiba, Ewa Kurzejamska, Michał Ławiński, Jarosław Olav Horbańczuk, Jakub Radziszewski, Karolina Fraczek, Renata Wolinska, Justyna Paszkiewicz, Piotr Religa, Mariusz Sacharczuk. The Journey of Cancer Cells to the Brain: Challenges and OpportunitiesInternational Journal of Molecular Sciences 2023; 24(4): 3854 doi: 10.3390/ijms24043854
2
Sekaran Saravanan, Selvaraj Vimalraj, Koka Pavani, Ramesh Nikarika, Venil N. Sumantran. Intussusceptive angiogenesis as a key therapeutic target for cancer therapyLife Sciences 2020; 252: 117670 doi: 10.1016/j.lfs.2020.117670
3
Megumi Yokoyama. Alterations in Stromal Reaction During Tumor Progression in Oral MucosaJournal of Hard Tissue Biology 2011; 20(1): 23 doi: 10.2485/jhtb.20.23
4
Chengwei Gu, Sha Huang, Dongyun Gao, Yan Wu, Jiwei Li, Kui Ma, Xu Wu, Xiaobing Fu. Angiogenic Effect of Mesenchymal Stem Cells as a Therapeutic Target for Enhancing Diabetic Wound HealingThe International Journal of Lower Extremity Wounds 2014; 13(2): 88 doi: 10.1177/1534734614534977
5
Abdulhakim Umar Toro, Sudheesh K. Shukla, Parveen Bansal. Micronome Revealed miR-205-5p as Key Regulator of VEGFA During Cancer Related Angiogenesis in Hepatocellular CarcinomaMolecular Biotechnology 2023; 65(7): 1178 doi: 10.1007/s12033-022-00619-5
6
Josh Neman, Amanda Hambrecht, Cherie Cadry, Amir Goodarzi, Jonathan Youssefzadeh, Mike Y. Chen, Rahul Jandial. Regenerative Biology of the Spine and Spinal CordAdvances in Experimental Medicine and Biology 2012; 760: 174 doi: 10.1007/978-1-4614-4090-1_11
7
Wei Kang Cheng, Chern Ein Oon. How glycosylation aids tumor angiogenesis: An updated reviewBiomedicine & Pharmacotherapy 2018; 103: 1246 doi: 10.1016/j.biopha.2018.04.119
8
Asim Kurjak, Sonal Panchal. Three-dimensional Ultrasound and Ovarian CancerDonald School Journal of Ultrasound in Obstetrics and Gynecology 2022; 16(3): 250 doi: 10.5005/jp-journals-10009-1940
9
Prasad V. Pawar, Abraham J. Domb, Neeraj Kumar. Focal Controlled Drug DeliveryAdvances in Delivery Science and Technology 2014; : 61 doi: 10.1007/978-1-4614-9434-8_3
10
Zhi Huang, Shi-Deng Bao. Roles of main pro- and anti-angiogenic factors in tumor angiogenesisWorld Journal of Gastroenterology 2004; 10(4): 463-470 doi: 10.3748/wjg.v10.i4.463
11
Mei-Lang Kung, Shih-Tsung Huang, Kuo-Wang Tsai, Tian-Huei Chu, Shuchen Hsieh. Nanosized zingerone-triggered anti-angiogenesis contributes to tumor suppression in human hepatocellular carcinomaColloids and Surfaces A: Physicochemical and Engineering Aspects 2023; 658: 130697 doi: 10.1016/j.colsurfa.2022.130697
12
Monica SM Chan, Lin Wang, Niramol Chanplakorn, Kentaro Tamaki, Takayuki Ueno, Masakazu Toi, Wings TY Loo, Louis WC Chow, Takashi Suzuki, Hironobu Sasano. Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma – an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapyExpert Opinion on Therapeutic Targets 2012; 16(sup1): S69 doi: 10.1517/14728222.2011.628938
13
Alessia Petronelli, Gaetano Pannitteri, Ugo Testa. Triterpenoids as new promising anticancer drugsAnti-Cancer Drugs 2009; 20(10): 880 doi: 10.1097/CAD.0b013e328330fd90
14
Daria Stepanova, Helen M. Byrne, Philip K. Maini, Tomás Alarcón, Roeland M.H. Merks. A multiscale model of complex endothelial cell dynamics in early angiogenesisPLOS Computational Biology 2021; 17(1): e1008055 doi: 10.1371/journal.pcbi.1008055
15
Xin Li, Gan-Sheng Feng, Chuan-Sheng Zheng, Chen-Kai Zhuo, Xi Liu. Expression of plasma vascular endothelial growth factor in patients with hepatocellular carcinoma and effect of transcatheter arterial chemoembolization therapy on plasma vascular endothelial growth factor levelWorld Journal of Gastroenterology 2004; 10(19): 2878-2882 doi: 10.3748/wjg.v10.i19.2878
16
Tatsuya Yoshihara, Fumi Takahashi-Yanaga, Fumie Shiraishi, Sachio Morimoto, Yutaka Watanabe, Masato Hirata, Sumio Hoka, Toshiyuki Sasaguri. Anti-angiogenic effects of differentiation-inducing factor-1 involving VEGFR-2 expression inhibition independent of the Wnt/β-catenin signaling pathwayMolecular Cancer 2010; 9(1) doi: 10.1186/1476-4598-9-245
17
M. Puisoru, C. Fatu, I.C. Fatu. Histochemical evaluation of angiogenesis in endometrial adenocarcinomaAnnals of Anatomy - Anatomischer Anzeiger 2006; 188(3): 255 doi: 10.1016/j.aanat.2005.11.014
18
Masoud Homayouni Tabrizi, Seyed Mohammad Reza Seyedi, Zeynab Mokhtareeizadeh. The anticancer activity of metal oxides and phytochemical-enriched medicinal nano-spheres (MNS); a comparative evaluationInorganic and Nano-Metal Chemistry 2022; 52(6): 890 doi: 10.1080/24701556.2021.1956953
19
Lidia Kria, Taoufik Khalfaoui, Ghada Mkannez, Omar Beltaief, Raja Anane, Khalil Errais, Lilia Tounsi, Raja Zhioua, Sarra Ben Jilani, Amel Meddeb Ouertani. Immunohistochemical study of vascular endothelial growth factor (VEGF), tumor suppressor protein (p53) and intercellular adhesion molecule (ICAM-1) in the conjunctiva of diabetic patientsJournal of Molecular Histology 2006; 36(6-7): 381 doi: 10.1007/s10735-005-9002-9
20
Monica Sm Chan, Lin Wang, Saulo Ja Felizola, Takayuki Ueno, Masakazu Toi, W Loo, Louis Wc Chow, Takashi Suzuki, Hironobu Sasano. Changes of tumor infiltrating lymphocyte subtypes before and after neoadjuvant endocrine therapy in estrogen receptor-positive breast cancer patients – an immunohistochemical study of cd8+ and foxp3+ using double immunostaining with correlation to the pathobiological response of the patientsThe International Journal of Biological Markers 2012; 27(4): 295 doi: 10.5301/JBM.2012.10439
21
DAN-DAN YUAN, ZHONG-XIU ZHU, XIA ZHANG, JIE LIU. Targeted therapy for gastric cancer: Current status and future directions (Review)Oncology Reports 2016; 35(3): 1245 doi: 10.3892/or.2015.4528
22
S Serratì, F Margheri, G Fibbi, G Di Cara, L Minafra, I Pucci‐Minafra, F Liotta, F Annunziato, M Pucci, M Del Rosso. Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR‐4‐dependent up‐regulation of urokinase‐type plasminogen activator receptor (uPAR, CD87) expressionThe Journal of Pathology 2008; 214(5): 545 doi: 10.1002/path.2309
23
Aeyung Kim, Minju Im, Nam-Hui Yim, Jin Yeul Ma. Reduction of metastatic and angiogenic potency of malignant cancer by Eupatorium fortunei via suppression of MMP-9 activity and VEGF productionScientific Reports 2014; 4(1) doi: 10.1038/srep06994
24
Manuela Banciu, Raymond M. Schiffelers, Marcel H.A.M. Fens, Josbert M. Metselaar, Gert Storm. Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in miceJournal of Controlled Release 2006; 113(1): 1 doi: 10.1016/j.jconrel.2006.03.019
25
Donia Sadri, Sareh Farhadi, Pegah Nourmohamadi. Angiogenesis in odontogenic keratocyst and dentigerous cyst: Evaluation of JunB and VEGF expressionDental Research Journal 2019; 16(5): 327 doi: 10.4103/1735-3327.266092
26
Mohamed El-Tanani, Hamdi Nsairat, Vijay Mishra, Yachana Mishra, Alaa A. A. Aljabali, Ángel Serrano-Aroca, Murtaza M. Tambuwala. Ran GTPase and Its Importance in Cellular Signaling and Malignant PhenotypeInternational Journal of Molecular Sciences 2023; 24(4): 3065 doi: 10.3390/ijms24043065
27
Lulian Pang, Chen Gan, Jian Xu, Yingxue Jia, Jiaying Chai, Runze Huang, Anlong Li, Han Ge, Sheng Yu, Huaidong Cheng. Bone Metastasis of Breast Cancer: Molecular Mechanisms and Therapeutic StrategiesCancers 2022; 14(23): 5727 doi: 10.3390/cancers14235727
28
Sana Ahuja, Sufian Zaheer. Multifaceted TGF‐β signaling, a master regulator: From bench‐to‐bedside, intricacies, and complexitiesCell Biology International 2024; 48(2): 87 doi: 10.1002/cbin.12097
29
Minju Im, Aeyung Kim, Jin Yeul Ma. Ethanol extract of baked Gardeniae Fructus exhibits in vitro and in vivo anti-metastatic and anti-angiogenic activities in malignant cancer cells: Role of suppression of the NF-κB and HIF-1α pathwaysInternational Journal of Oncology 2016; 49(6): 2377 doi: 10.3892/ijo.2016.3742
30
Roberta Lugano, Mohanraj Ramachandran, Anna Dimberg. Tumor angiogenesis: causes, consequences, challenges and opportunitiesCellular and Molecular Life Sciences 2020; 77(9): 1745 doi: 10.1007/s00018-019-03351-7
31
Davood Rezazadeh, Roghayeh Anvari Aliabad, Amir Hossein Norooznezhad. Autologous amniotic membrane: An accelerator of wound healing for prevention of surgical site infections following Cesarean deliveryMedical Hypotheses 2020; 137: 109532 doi: 10.1016/j.mehy.2019.109532
32
Nan Li, Bin Chen, Run Lin, Ni Liu, Hai-tao Dai, Ke-yu Tang, Jian-yong Yang, Yong-hui Huang. The earlier, the better: the effects of different administration timepoints of sorafenib in suppressing the carcinogenesis of VEGF in ratsCancer Chemotherapy and Pharmacology 2018; 81(1): 207 doi: 10.1007/s00280-017-3493-4
33
Sung Yi Hong, Myun Hee Lee, Kyung Sup Kim, Hyun Cheol Jung, Jae Kyung Roh, Woo Jin Hyung, Sung Hoon Noh, Seung Ho Choi. Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse modelWorld Journal of Gastroenterology 2004; 10(8): 1191-1197 doi: 10.3748/wjg.v10.i8.1191
34
Wenfeng Zhang, Cun Liu, Jie Li, Yiping Lu, Huayao Li, Jing Zhuang, Xin Ren, Mengmeng Wang, Changgang Sun. Tanshinone IIA: New Perspective on the Anti-Tumor Mechanism of A Traditional Natural MedicineThe American Journal of Chinese Medicine 2022; 50(01): 209 doi: 10.1142/S0192415X22500070
35
Guangying Zhou, Yanting Zhang, Abolfazl Akbari, Xin Wang, Jing Wei. EF-24, a Curcumin Analogue, Could Inhibit HSP90 and Induce Apoptosis-Mediated by Autophagy/Inflammation/Oxidative Stress in Papillary Thyroid Cancer Cell LinesNatural Product Communications 2023; 18(4): 1934578X2311667 doi: 10.1177/1934578X231166784
36
Amira M. Gamal-Eldeen, Dina Moustafa, Sherien M. El-Daly, Mona A.M. Abo-Zeid, Samira Saleh, Menka Khoobchandani, Kavita Katti, Ravi Shukla, Kattesh V. Katti. Gum Arabic-encapsulated gold nanoparticles for a non-invasive photothermal ablation of lung tumor in miceBiomedicine & Pharmacotherapy 2017; 89: 1045 doi: 10.1016/j.biopha.2017.03.006
37
Dong Lv, Pei-Lin Cui, Shi-Wei Yao, You-Qing Xu, Zhao-Xu Yang. Melatonin inhibits the expression of vascular endothelial growth factor in pancreatic cancer cellsChinese Journal of Cancer Research 2012; 24(4): 310 doi: 10.1007/s11670-012-0269-6
38
Sílvia Coma, Veronique Noe, Cinzia Lavarino, Jaume Adán, Manuel Rivas, Mariana López-Matas, Roser Pagan, Francesc Mitjans, Senén Vilaró, Jaume Piulats, Carlos J. Ciudad. Use of siRNAs and Antisense Oligonucleotides Against Survivin RNA to Inhibit Steps Leading to Tumor AngiogenesisOligonucleotides 2004; 14(2): 100 doi: 10.1089/1545457041526290
39
Naina Kumari, Sagar Bhandari, Anzal Ishfaq, Samia Rauf R Butt , Chukwuyem Ekhator , Amanda Karski , Bijan Kadel, Mohamedalamin Alnoor Altayb Ismail , Tenzin N Sherpa, Ahmed Al Khalifa, Bashar Khalifah, Nhan Nguyen, Slobodan Lazarevic, Mohammad Uzair Zaman, Ashraf Ullah, Vikas Yadav. Primary Cardiac Angiosarcoma: A ReviewCureus 2023;  doi: 10.7759/cureus.41947
40
Zainab Arshad, John F. McDonald. Changes in gene-gene interactions associated with cancer onset and progression are largely independent of changes in gene expressioniScience 2021; 24(12): 103522 doi: 10.1016/j.isci.2021.103522
41
Phei Er Saw, Erwei Song. Tumor Ecosystem2023; : 125 doi: 10.1007/978-981-99-1183-7_6
42
Abhinav Agarwal, Abhay Asthana, Umesh Gupta, Narendra K Jain. Tumour and dendrimers: a review on drug delivery aspectsJournal of Pharmacy and Pharmacology 2010; 60(6): 671 doi: 10.1211/jpp.60.6.0001
43
Pezhman Shiri, Sorour Ramezanpour, Ali Mohammad Amani, Wim Dehaen. A patent review on efficient strategies for the total synthesis of pazopanib, regorafenib and lenvatinib as novel anti-angiogenesis receptor tyrosine kinase inhibitors for cancer therapyMolecular Diversity 2022; 26(5): 2981 doi: 10.1007/s11030-022-10406-8
44
Inna Rabinovich-Nikitin, Lorrie A Kirshenbaum. BMAL1 regulates cell cycle progression and angiogenesis of endothelial cellsCardiovascular Research 2023; 119(10): 1889 doi: 10.1093/cvr/cvad103
45
Mohammad Mahboubi-Rabbani, Rosa Zarei, Mehdi Baradaran, Maryam Bayanati, Afshin Zarghi. Chalcones as Potential Cyclooxygenase-2 Inhibitors: A ReviewAnti-Cancer Agents in Medicinal Chemistry 2024; 24(2): 77 doi: 10.2174/0118715206267309231103053808
46
Omar Saeed Ali Al-Salahi, Dan Ji, Amin Malik Shah Abdul Majid, Chan Kit-Lam, Wan Zaidah Abdullah, Abdelhamid Zaki, Shah Kamal Khan Jamal Din, Narazah Mohd Yusoff, Aman Shah Abdul Majid, Salvatore V. Pizzo. Anti-Tumor Activity of Eurycoma longifolia Root Extracts against K-562 Cell Line: In Vitro and In Vivo StudyPLoS ONE 2014; 9(1): e83818 doi: 10.1371/journal.pone.0083818
47
Nabil F. Saba, Pooja Vijayvargiya, Jan B. Vermorken, Juan P. Rodrigo, Stefan M. Willems, Nina Zidar, Remco de Bree, Antti Mäkitie, Greg T. Wolf, Athanassios Argiris, Yong Teng, Alfio Ferlito. Targeting Angiogenesis in Squamous Cell Carcinoma of the Head and Neck: Opportunities in the Immunotherapy EraCancers 2022; 14(5): 1202 doi: 10.3390/cancers14051202
48
Erika Olivia Gómez, Yolanda Irasema Chirino, Norma Laura Delgado-Buenrostro, Alejandro López-Saavedra, Noemí Meraz-Cruz, Rebeca López-Marure. Secretome derived from breast tumor cell lines alters the morphology of human umbilical vein endothelial cellsMolecular Membrane Biology 2016; 33(1-2): 29 doi: 10.1080/09687688.2016.1229057
49
Seong Keun Kim, Sun Wook Cho. The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor MicroenvironmentFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.868695
50
SHAYMA KHAN, NAINA DUBEY, BASANT KHARE, HARSHITA JAIN, PRATEEK KUMAR JAIN. PREPARATION AND CHARACTERIZATION OF ALGINATE CHITOSAN CROSSLINKED NANOPARTICLES BEARING DRUG FOR THE EFFECTIVE MANAGEMENT OF ULCERATIVE COLITISInternational Journal of Current Pharmaceutical Research 2022; : 48 doi: 10.22159/ijcpr.2022v14i5.2040
51
Mary Ann Stevenson, Stuart K. Calderwood. Clinical Radiation Oncology2012; : 43 doi: 10.1016/B978-1-4377-1637-5.00002-X
52
Majiong Jiang, Riccardo Ferdani, Monica Shokeen, Carolyn J. Anderson. Comparison of two cross-bridged macrocyclic chelators for the evaluation of 64Cu-labeled-LLP2A, a peptidomimetic ligand targeting VLA-4-positive tumorsNuclear Medicine and Biology 2013; 40(2): 245 doi: 10.1016/j.nucmedbio.2012.10.010
53
Nozomi Ami, Hideki Sato, Yoshihiro Hayakawa. Paclitaxel-induced hypothermia and hypoperfusion increase breast cancer metastasis and angiogenesis in miceOncology Letters 2017;  doi: 10.3892/ol.2017.7621
54
Soo Mi Ki, Ji Hyun Kim, So Yeon Won, Shin Ji Oh, In Young Lee, Young‐Ki Bae, Ki Wha Chung, Byung‐Ok Choi, Boyoun Park, Eui‐Ju Choi, Ji Eun Lee. CEP41‐mediated ciliary tubulin glutamylation drives angiogenesis through AURKA‐dependent deciliationEMBO reports 2020; 21(2) doi: 10.15252/embr.201948290
55
Dalei Chen, Zhijian Wu, Lu-Ning Wu, Jingtao Jiang, Gui-Nv Hu. Theaflavin Attenuates TBHP-Induced Endothelial Cells Oxidative Stress by Activating PI3K/AKT/Nrf2 and Accelerates Wound Healing in RatsFrontiers in Bioengineering and Biotechnology 2022; 10 doi: 10.3389/fbioe.2022.830574
56
Xin Luo, Wei Zou, Zhonghong Wei, Suyun Yu, Yang Zhao, Yuanyuan Wu, Aiyun Wang, Yin Lu. Inducing vascular normalization: A promising strategy for immunotherapyInternational Immunopharmacology 2022; 112: 109167 doi: 10.1016/j.intimp.2022.109167
57
Suyeong Seo, Seung‐Yeol Nah, Kangwon Lee, Nakwon Choi, Hong Nam Kim. Triculture Model of In Vitro BBB and its Application to Study BBB‐Associated Chemosensitivity and Drug Delivery in GlioblastomaAdvanced Functional Materials 2022; 32(10) doi: 10.1002/adfm.202106860
58
Tao Feng, Yanli Zhao. Nanomaterial-Based Drug Delivery Carriers for Cancer TherapySpringerBriefs in Applied Sciences and Technology 2017; : 1 doi: 10.1007/978-981-10-3299-8_1
59
Andresa Borges Soares, Albina Alternarli, Thais Ribeiro De Oliveira, Felipe de Oliveira Fonseca Rodrigues, Alfredo Ribeiro-Silva, Danilo Figueiredo Soave, Fabricio Passador-Santos, Suellen Trentin Brum, Marcelo Henrique Napimoga, Vera Cavalcanti De Araújo. Comparison of the Blood and Lymphatic Microvessel Density of Pleomorphic Adenoma and Basal Cell AdenomaClinical Medicine Insights: Pathology 2015; 8: CPath.S23035 doi: 10.4137/CPath.S23035
60
Alena Liskova, Lenka Koklesova, Marek Samec, Elizabeth Varghese, Mariam Abotaleb, Samson Mathews Samuel, Karel Smejkal, Kamil Biringer, Martin Petras, Dana Blahutova, Ondrej Bugos, Martin Pec, Marian Adamkov, Dietrich Büsselberg, Rachele Ciccocioppo, Mariusz Adamek, Luis Rodrigo, Martin Caprnda, Peter Kruzliak, Peter Kubatka. Implications of flavonoids as potential modulators of cancer neovascularityJournal of Cancer Research and Clinical Oncology 2020; 146(12): 3079 doi: 10.1007/s00432-020-03383-8
61
Saurabh Singh, Sanjay Pandey, Amanpreet Singh Chawla, Anant Narayan Bhatt, Bal Gangadhar Roy, Daman Saluja, Bilikere S. Dwarakanath. Dietary 2-deoxy-D-glucose impairs tumour growth and metastasis by inhibiting angiogenesisEuropean Journal of Cancer 2019; 123: 11 doi: 10.1016/j.ejca.2019.09.005
62
Mohsen Akbarian, Luiz E. Bertassoni, Lobat Tayebi. Biological aspects in controlling angiogenesis: current progressCellular and Molecular Life Sciences 2022; 79(7) doi: 10.1007/s00018-022-04348-5
63
Yao Wendong, Jiang Jiali, Fan Qiaomei, Weng Yayun, Xie Xianze, Shi Zheng, Huang Wei. Biomechanical forces and force-triggered drug delivery in tumor neovascularizationBiomedicine & Pharmacotherapy 2024; 171: 116117 doi: 10.1016/j.biopha.2023.116117
64
Bo Tian, Yuhang Xiao, Junliang Ma, Wei Ou, Hui Wang, Jie Wu, Jinming Tang, Baihua Zhang, Xiaojuan Liao, Desong Yang, Zhining Wu, Xu Li, Yong Zhou, Min Su, Wenxiang Wang. <p>Parthenolide Inhibits Angiogenesis in Esophageal Squamous Cell Carcinoma Through Suppression of VEGF</p>OncoTargets and Therapy 2020; : 7447 doi: 10.2147/OTT.S256291
65
Miao Li, Xi Zhang, Mimi Wang, Yaohui Wang, Jiali Qian, Xiaoxia Xing, Zhiming Wang, Yang You, Kun Guo, Jie Chen, Dongmei Gao, Yan Zhao, Lan Zhang, Rongxin Chen, Jiefeng Cui, Zhenggang Ren. Activation of Piezo1 contributes to matrix stiffness‐induced angiogenesis in hepatocellular carcinomaCancer Communications 2022; 42(11): 1162 doi: 10.1002/cac2.12364
66
Miao Li, Ying-Ying Zhao, Jie-Feng Cui. Matrix stiffness in regulation of tumor angiogenesisWorld Chinese Journal of Digestology 2022; 30(20): 871 doi: 10.11569/wcjd.v30.i20.871
Abstract() |  Core Tip() |  Full Article(HTML)() | Times Cited  (0) | Total Visits (0) | Open
67
N. Sarkar, S. De, M. Das, T. Saha, S. Banerjee, S. K. Ashok Kumar, Y.-C. Kuo. Insights of Indole: A Novel Target in Medicinal Chemistry (A Review)Russian Journal of General Chemistry 2023; 93(7): 1791 doi: 10.1134/S1070363223070216
68
Vandana Golhani, Suman Kumar Ray, Sukhes Mukherjee. Role of MicroRNAs and Long Non-Coding RNAs in Regulating Angiogenesis in Human Breast Cancer: A Molecular Medicine PerspectiveCurrent Molecular Medicine 2022; 22(10): 882 doi: 10.2174/1566524022666211217114527
69
Yaning Wang, Zhuo Zhang, Zhaohua Cheng, Wei Xie, Hanjiao Qin, Jiyao Sheng. Astragaloside in cancer chemoprevention and therapyChinese Medical Journal 2023; 136(10): 1144 doi: 10.1097/CM9.0000000000002661
70
Geetika Kaur, Bipradas Roy. Decoding Tumor Angiogenesis for Therapeutic Advancements: Mechanistic InsightsBiomedicines 2024; 12(4): 827 doi: 10.3390/biomedicines12040827
71
Ren-Yi Qin, Ru-Liang Fang, Manoj Kumar Gupta, Zheng-Ren Liu, Da-Yu Wang, Qing Chang, Yi-Bei Chen. Alteration of somatostatin receptor subtype 2 gene expression in pancreatic tumor angiogenesisWorld Journal of Gastroenterology 2004; 10(1): 132-135 doi: 10.3748/wjg.v10.i1.132
72
Honghe Luo, Zhenguang Chen, Hui Jin, Mei Zhuang, Tao Wang, Chunhua Su, Yiyan Lei, Jianyong Zou, Beilong Zhong. Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancerJournal of Experimental & Clinical Cancer Research 2011; 30(1) doi: 10.1186/1756-9966-30-6
73
Michael A Gordon, Ji Gil, Bo Lu, Wu Zhang, Dongyun Yang, Jim Yun, Sylke Schneider, Susan Groshen, Syma Iqbal, Oliver A Press, Katrin Rhodes, Heinz-Josef Lenz. Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiationPharmacogenomics 2006; 7(1): 67 doi: 10.2217/14622416.7.1.67
74
Jae‐Won Kim, Seok‐Yun Jung, Yi‐Hong Kwon, Sang‐Hun Lee, Jun‐Hee Lee, Boo‐Yong Lee, Sang‐Mo Kwon. Ginsenoside Rg3 Inhibits Endothelial Progenitor Cell Differentiation through Attenuation of VEGF‐Dependent Akt/eNOS SignalingPhytotherapy Research 2012; 26(9): 1286 doi: 10.1002/ptr.3722
75
Prashant Puttagunta, Saagar V. Pamulapati, James E. Bates, Jennifer H. Gross, William A. Stokes, Nicole C. Schmitt, Conor Steuer, Yong Teng, Nabil F. Saba. Critical review of the current and future prospects of VEGF-TKIs in the management of squamous cell carcinoma of head and neckFrontiers in Oncology 2023; 13 doi: 10.3389/fonc.2023.1310106
76
Pei-Yin Ho, Sung-Po Hsu, Yu-Chih Liang, Min-Liang Kuo, Yuan-Soon Ho, Wen-Sen Lee. Inhibition of the ERK phosphorylation plays a role in terbinafine-induced p21 up-regulation and DNA synthesis inhibition in human vascular endothelial cellsToxicology and Applied Pharmacology 2008; 229(1): 86 doi: 10.1016/j.taap.2007.12.028
77
Cho-Won Kim, Hong Kyu Lee, Min-Woo Nam, Gabsang Lee, Kyung-Chul Choi. The Role of <i>KiSS1</i> Gene on the Tumor Growth and Migration of Prostate Cancer and the Underlying Molecular MechanismsSSRN Electronic Journal 2022;  doi: 10.2139/ssrn.4153272
78
Sanjib Bhattacharyya, Rachel A. Kudgus, Resham Bhattacharya, Priyabrata Mukherjee. Inorganic Nanoparticles in Cancer TherapyPharmaceutical Research 2011; 28(2): 237 doi: 10.1007/s11095-010-0318-0
79
Manjusha Dixit, Vinay J, Soham Choudhury. Gallbladder Cancer2023; : 291 doi: 10.1007/978-981-19-6442-8_16
80
Ahmad Hoseinzadeh, Hamed Ghoddusi Johari, Mohammad Hossein Anbardar, Lobat Tayebi, Ehsan Vafa, Milad Abbasi, Ahmad Vaez, Ali Golchin, Ali Mohammad Amani, Ali Jangjou. Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic processEuropean Journal of Medical Research 2022; 27(1) doi: 10.1186/s40001-022-00833-6
81
Nathalie Schleich, Chrystelle Po, Damien Jacobs, Bernard Ucakar, Bernard Gallez, Fabienne Danhier, Véronique Préat. Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapyJournal of Controlled Release 2014; 194: 82 doi: 10.1016/j.jconrel.2014.07.059
82
Aeyung Kim, Minju Im, Min Jung Gu, Jin Yeul Ma. Ethanol extract of Lophatheri Herba exhibits anti-cancer activity in human cancer cells by suppression of metastatic and angiogenic potentialScientific Reports 2016; 6(1) doi: 10.1038/srep36277
83
Ji Wang, Jianli Yang, Dawei Yuan, Jun Wang, Jia Zhao, Li Wang. Effects of basic fibroblast growth factor on angiogenin expression and cell proliferation in H7402 human hepatoma cellsJournal of Genetics and Genomics 2009; 36(7): 399 doi: 10.1016/S1673-8527(08)60129-0
84
Syed Faheem Askari Rizvi, Shuai Mu, Yaya Wang, Shuangqin Li, Haixia Zhang. Fluorescent RGD-based pro-apoptotic peptide conjugates as mitochondria-targeting probes for enhanced anticancer activitiesBiomedicine & Pharmacotherapy 2020; 127: 110179 doi: 10.1016/j.biopha.2020.110179
85
J. Anakha, Prakashkumar Dobariya, Shyam Sunder Sharma, Abhay H. Pande. Recombinant human endostatin as a potential anti-angiogenic agent: therapeutic perspective and current statusMedical Oncology 2023; 41(1) doi: 10.1007/s12032-023-02245-w
86
Byung‐Hee Chung, Young‐Lai Cho, Jong‐Dai Kim, Heui Sug Jo, Moo‐Ho Won, Hansoo Lee, Kwon‐Soo Ha, Young‐Geun Kwon, Young‐Myeong Kim. Promotion of direct angiogenesis in vitro and in vivo by Puerariae flos extract via activation of MEK/ERK‐, PI3K/Akt/eNOS‐, and Src/FAK‐dependent pathwaysPhytotherapy Research 2010; 24(6): 934 doi: 10.1002/ptr.3063
87
Ching-Chuan Su, Chau-Jong Wang, Kai-Hsun Huang, Yi-Ju Lee, Wei-Ming Chan, Yun-Ching Chang. Anthocyanins from Hibiscus sabdariffa calyx attenuate in vitro and in vivo melanoma cancer metastasisJournal of Functional Foods 2018; 48: 614 doi: 10.1016/j.jff.2018.07.032
88
Xiaoyan Xu, Yao Zong, Yunxia Gao, Xiangrong Sun, Han Zhao, Wenjuan Luo, Shaoyou Jia. VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal PathwayBioMed Research International 2019; 2019: 1 doi: 10.1155/2019/3909102
89
Fatemeh Zahedipour, Parvin Zamani, Khadijeh Jamialahmadi, Mahmoud Reza Jaafari, Amirhossein Sahebkar. Vaccines targeting angiogenesis in melanomaEuropean Journal of Pharmacology 2021; 912: 174565 doi: 10.1016/j.ejphar.2021.174565
90
Tetsuya Nomura, Naoki Utoguchi. Development of cancer immunotherapy targeting tumor blood vesselsDrug Delivery System 2017; 32(3): 192 doi: 10.2745/dds.32.192
91
John T. Nardini, Bernadette J. Stolz, Kevin B. Flores, Heather A. Harrington, Helen M. Byrne, Mark Chaplain. Topological data analysis distinguishes parameter regimes in the Anderson-Chaplain model of angiogenesisPLOS Computational Biology 2021; 17(6): e1009094 doi: 10.1371/journal.pcbi.1009094
92
Qing Zhang, Yao-Xing Guo, Wan-Lin Zhang, Hai-Yan Lian, Natasha Iranzad, Endi Wang, Ying-Chun Li, Hai-Chao Tong, Le-Yao Li, Ling-Yun Dong, Lian-He Yang, Shuang Ma. Intra-tumoral angiogenesis correlates with immune features and prognosis in gliomaAging 2022; 14(10): 4402 doi: 10.18632/aging.204079
93
Arnd Heiligenhaus, Carsten Heinz, Klaus Schmitz, Christoph Tappeiner, Dirk Bauer, Daniel Meller. Cornea and External Eye DiseaseEssentials in Ophthalmology 2008; : 15 doi: 10.1007/978-3-540-33681-5_2
94
Fares Hezam Al-Ostoot, Salma Salah, Hussien Ahmed Khamees, Shaukath Ara Khanum. Tumor angiogenesis: Current challenges and therapeutic opportunitiesCancer Treatment and Research Communications 2021; 28: 100422 doi: 10.1016/j.ctarc.2021.100422
95
Tingting Huang, Hong Qiu, Xianglin Yuan. Targeted therapy of gastric cancer: current and prospective strategies*Oncology and Translational Medicine 2018; 4(2): 41 doi: 10.1007/s10330-018-0263-3
96
Lingyan Shi, Yihui Shen, Wei Min. Invited Article: Visualizing protein synthesis in mice with in vivo labeling of deuterated amino acids using vibrational imagingAPL Photonics 2018; 3(9) doi: 10.1063/1.5028134
97
Jian-hai Guo, Xu Zhu, Xiao-ting Li, Ren-jie Yang. Impact of serum vascular endothelial growth factor on prognosis in patients with unresectable hepatocellular carcinoma after transarterial chemoembolizationChinese Journal of Cancer Research 2012; 24(1): 36 doi: 10.1007/s11670-012-0036-8
98
Weilin Zhao, Ning Ma, Shumin Wang, Yingxi Mo, Zhe Zhang, Guangwu Huang, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa, Mariko Murata, Kazuhiko Takeuchi. RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinomaJournal of Experimental & Clinical Cancer Research 2017; 36(1) doi: 10.1186/s13046-017-0554-9
99
Iratxe Zuazo-Gaztelu, Oriol Casanovas. Tumor Angiogenesis2019; : 3 doi: 10.1007/978-3-319-33673-2_1
100
Chitta Ranjan Patra, Resham Bhattacharya, Debabrata Mukhopadhyay, Priyabrata Mukherjee. Application of Gold Nanoparticles for Targeted Therapy in CancerJournal of Biomedical Nanotechnology 2008; 4(2): 99 doi: 10.1166/jbn.2008.016
101
Heng-Ching Wen, Chieh Kao, Ruei-Chi Hsu, Yen-Nien Huo, Pei-Ching Ting, Li-Ching Chen, Sung-Po Hsu, Shu-Hui Juan, Wen-Sen Lee, Rajesh Mohanraj. Thy-1-Induced Migration Inhibition in Vascular Endothelial Cells through Reducing the RhoA ActivityPLoS ONE 2013; 8(4): e61506 doi: 10.1371/journal.pone.0061506
102
Sara Abdolmaleki, Alireza Aliabadi, Samad Khaksar. Riding the metal wave: A review of the latest developments in metal-based anticancer agentsCoordination Chemistry Reviews 2024; 501: 215579 doi: 10.1016/j.ccr.2023.215579
103
Fujun Dai, Lei Gao, Yuan Zhao, Chaojie Wang, Songqiang Xie. Farrerol inhibited angiogenesis through Akt/mTOR, Erk and Jak2/Stat3 signal pathwayPhytomedicine 2016; 23(7): 686 doi: 10.1016/j.phymed.2016.03.008
104
Romina Oglio, Federico Buschittari, Leonardo Salvarredi, Jennifer Michaux, Carla Rodriguez, Marina Perona, Alejandra Dagrosa, Guillermo Juvenal, Lisa Thomasz. 6 Iodo-delta lactone inhibits angiogenesis in human HT29 colon adenocarcinoma xenograft.Prostaglandins, Leukotrienes and Essential Fatty Acids 2022; 186: 102507 doi: 10.1016/j.plefa.2022.102507
105
Hua Wei, Yan Li, Qiang Ning, Zhi‑Min Suo. Regulation of miR‑155 affects the invasion and migration of gastric carcinoma cells by modulating the STAT3 signaling pathwayOncology Letters 2018;  doi: 10.3892/ol.2018.9152
106
Yuetong Wang, Mengge Huang, Xintong Zhou, Huayao Li, Xiaoran Ma, Changgang Sun. Potential of natural flavonoids to target breast cancer angiogenesis (review)British Journal of Pharmacology 2024;  doi: 10.1111/bph.16275
107
Venkatesh Katari, Kesha Dalal, Ravi K. Adapala, Brianna D. Guarino, Narendrababu Kondapalli, Sailaja Paruchuri, Charles K. Thodeti. Comprehensive Physiology2024; : 5389 doi: 10.1002/cphy.c230014
108
Jasmina Profirovic, Elena Strekalova, Norifumi Urao, Aleksandar Krbanjevic, Alexandra V. Andreeva, Sudhahar Varadarajan, Tohru Fukai, René Hen, Masuko Ushio-Fukai, Tatyana A. Voyno-Yasenetskaya. A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptorAngiogenesis 2013; 16(1): 15 doi: 10.1007/s10456-012-9296-7
109
T. Makinde, D.K. Agrawal. Intra and extravascular transmembrane signalling of angiopoietin‐1‐Tie2 receptor in health and diseaseJournal of Cellular and Molecular Medicine 2008; 12(3): 810 doi: 10.1111/j.1582-4934.2008.00254.x
110
Manoj Kumar, Sunil Kumar Dhatwalia, D. K. Dhawan. Role of angiogenic factors of herbal origin in regulation of molecular pathways that control tumor angiogenesisTumor Biology 2016; 37(11): 14341 doi: 10.1007/s13277-016-5330-5
111
Min Kyoung Shin, Bo-Young Jang, Kyung-Bin Bu, Seung-Ho Lee, Dong-Hee Han, Jin Wook Oh, Jung-Suk Sung. De Novo Design of AC-P19M, a Novel Anticancer Peptide with Apoptotic Effects on Lung Cancer Cells and Anti-Angiogenic ActivityInternational Journal of Molecular Sciences 2022; 23(24): 15594 doi: 10.3390/ijms232415594
112
Amira M. Gamal-Eldeen, Amani A. Alrehaili, Afaf Alharthi, Hamsa J. Banjer, Bassem M. Raafat, Nahed M. Hawsawi. Perftoran improves Visudyne-photodynamic therapy via suppressing hypoxia pathway in murine lung cancerJournal of Radiation Research and Applied Sciences 2022; 15(1): 238 doi: 10.1016/j.jrras.2022.03.011
113
Ping Mu, Qing Liu, Rongliang Zheng. Biphasic regulation of H2O2 on angiogenesis implicated NADPH oxidaseCell Biology International 2010; 34(10): 1013 doi: 10.1042/CBI20090092
114
Ahmed W Moawad, Janio Szklaruk, Chandana Lall, Katherine J Blair, Ahmed O Kaseb, Amita Kamath, Scott A Rohren, Khaled M Elsayes. <p>Angiogenesis in Hepatocellular Carcinoma; Pathophysiology, Targeted Therapy, and Role of Imaging</p>Journal of Hepatocellular Carcinoma 2020; : 77 doi: 10.2147/JHC.S224471
115
Phuong Anh Do, Chang Hoon Lee. The Role of CDK5 in Tumours and Tumour MicroenvironmentsCancers 2020; 13(1): 101 doi: 10.3390/cancers13010101
116
Subhojit Paul, Tanmoy Mukherjee, Kaushik Das. Coagulation Protease-Driven Cancer Immune Evasion: Potential Targets for Cancer ImmunotherapyCancers 2024; 16(8): 1568 doi: 10.3390/cancers16081568
117
Woom-Yee Bae, Jae-Sun Choi, Ja-Eun Kim, Chan Park, Joo-Won Jeong. Zingerone suppresses angiogenesisviainhibition of matrix metalloproteinases during tumor developmentOncotarget 2016; 7(30): 47232 doi: 10.18632/oncotarget.10030
118
Jhansi Nathan, Rajaretinam Rajesh Kannan. Antiangiogenic molecules from marine actinomycetes and the importance of using zebrafish model in cancer researchHeliyon 2020; 6(12): e05662 doi: 10.1016/j.heliyon.2020.e05662
119
Pei-Yin Ho, Wen-Bin Zhong, Yuan-Soon Ho, Wen-Sen Lee. Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathwayMolecular Cancer Therapeutics 2006; 5(12): 3130 doi: 10.1158/1535-7163.MCT-06-0457
120
Rong Qiu, Soichiro Murata, Chao Cheng, Akihiro Mori, Yunzhong Nie, Satoshi Mikami, Shunsuke Hasegawa, Tomomi Tadokoro, Satoshi Okamoto, Hideki Taniguchi. A Novel Orthotopic Liver Cancer Model for Creating a Human-like Tumor MicroenvironmentCancers 2021; 13(16): 3997 doi: 10.3390/cancers13163997
121
Yanhong Pan, Weipeng Wu, Xiaoxin Jiang, Yunhong Liu. Mesenchymal stem cell-derived exosomes in cardiovascular and cerebrovascular diseases: From mechanisms to therapyBiomedicine & Pharmacotherapy 2023; 163: 114817 doi: 10.1016/j.biopha.2023.114817
122
Iratxe Zuazo-Gaztelu, Oriol Casanovas. Tumor Angiogenesis2016; : 1 doi: 10.1007/978-3-319-31215-6_1-1
123
Priyabrata Mukherjee, Resham Bhattacharya, Chitta Ranjan Patra, Debabrata Mukhopadhyay. Nanotechnologies for the Life Sciences2003;  doi: 10.1002/9783527610419.ntls0073
124
Kanakaraju Manupati, Ragini Yeeravalli, Komal Kaushik, Digvijay Singh, Bhupendra Mehra, Nitin Gangane, Anupama Gupta, Kalyan Goswami, Amitava Das. Activation of CD44-Lipoprotein lipase axis in breast cancer stem cells promotes tumorigenesisBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2021; 1867(11): 166228 doi: 10.1016/j.bbadis.2021.166228
125
Sheetal Parida, Mahitosh Mandal. Anti-Angiogenesis Drug Discovery and Development2014; : 3 doi: 10.1016/B978-0-12-803963-2.50001-6
126
Magdalena Szczerbowska-Boruchowska, Marek Lankosz, Mateusz Czyzycki, Dariusz Adamek. An integrated experimental and analytical approach to the chemical state imaging of iron in brain gliomas using X-ray absorption near edge structure spectroscopyAnalytica Chimica Acta 2011; 699(2): 153 doi: 10.1016/j.aca.2011.05.044
127
Enhanced permeability and retention effect-focused tumor-targeted nanomedicines: latest trends, obstacles and future perspectiveNanomedicine 2022; 17(18): 1213 doi: 10.2217/nnm-2022-0065
128
Jakub Toczek, Żaneta Jastrzębska-Stojko, Rafał Stojko, Agnieszka Drosdzol-Cop. Endometriosis: New Perspective for the Diagnosis of Certain Cytokines in Women and Adolescent Girls, as Well as the Progression of Disease Outgrowth: A Systematic ReviewInternational Journal of Environmental Research and Public Health 2021; 18(9): 4726 doi: 10.3390/ijerph18094726
129
Mingcheng Huang, Qian Qiu, Shan Zeng, Youjun Xiao, Maohua Shi, Yaoyao Zou, Yujin Ye, Liuqin Liang, Xiuyan Yang, Hanshi Xu. Niclosamide inhibits the inflammatory and angiogenic activation of human umbilical vein endothelial cellsInflammation Research 2015; 64(12): 1023 doi: 10.1007/s00011-015-0888-8
130
JaeWook Park, Hyunji Kim, Jeongwoo Ham, Wonjae Lee, Won-Gun Koh. Cell-adhesive double network self-healing hydrogel capable of cell and drug encapsulation: New platform to construct biomimetic environment with bottom-up approachCarbohydrate Polymers 2024; 338: 122204 doi: 10.1016/j.carbpol.2024.122204
131
Duy T. Nguyen, Elizabeth Ogando-Rivas, Ruixuan Liu, Theodore Wang, Jacob Rubin, Linchun Jin, Haipeng Tao, William W. Sawyer, Hector R. Mendez-Gomez, Matthew Cascio, Duane A. Mitchell, Jianping Huang, W. Gregory Sawyer, Elias J. Sayour, Paul Castillo. CAR T Cell Locomotion in Solid Tumor MicroenvironmentCells 2022; 11(12): 1974 doi: 10.3390/cells11121974
132
Gerard C. Krijger, Marjan M. Fretz, Ula D. Woroniecka, Olav M. Steinebach, Wim Jiskoot, Gert Storm, Gerben A. Koning. Tumor cell and tumor vasculature targeted liposomes for neutron capture therapyRadiochimica Acta 2005; 93(9-10): 589 doi: 10.1524/ract.2005.93.9-10.589
133
Manuela Banciu, Raymond M. Schiffelers, Josbert M. Metselaar, Gert Storm. Utility of Targeted Glucocorticoids in Cancer TherapyJournal of Liposome Research 2008; 18(1): 47 doi: 10.1080/08982100801893978
134
Anggraeni E. Kusumaningrum, Sarce Makaba, Eyhab Ali, Mandeep Singh, Mohammed N. Fenjan, Irodakhon Rasulova, Neeti Misra, Sada G. Al‐ Musawi, Ali Alsalamy. A perspective on emerging therapies in metastatic colorectal cancer: Focusing on molecular medicine and drug resistanceCell Biochemistry and Function 2024; 42(1) doi: 10.1002/cbf.3906
135
Chao Yan, Zheng-Gang Zhu, Ying-Yan Yu, Jun Ji, Yi Zhang, Yu-Bao Ji, Min Yan, Jun Chen, Bing-Ya Liu, Hao-Ran Yin, Yan-Zhen Lin. Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasisWorld Journal of Gastroenterology 2004; 10(6): 783-790 doi: 10.3748/wjg.v10.i6.783
136
Xin-Jie Niu, Zuo-Ren Wang, Sheng-Li Wu, Zhi-Min Geng, Yun-Feng Zhang, Xing-Lei Qing. Relationship between inducible nitric oxide synthase expression and angiogenesis in primary gallbladder carcinoma tissueWorld Journal of Gastroenterology 2004; 10(5): 725-728 doi: 10.3748/wjg.v10.i5.725
137
A. Mustafa, F. Elkhamisy, N. Arghiani, M.Z.I. Pranjol. Potential crosstalk between pericytes and cathepsins in the tumour microenvironmentBiomedicine & Pharmacotherapy 2023; 164: 114932 doi: 10.1016/j.biopha.2023.114932
138
Claudia T. Mierke. The Biomechanical Properties of 3d Extracellular Matrices and Embedded Cells Regulate the Invasiveness of Cancer CellsCell Biochemistry and Biophysics 2011; 61(2): 217 doi: 10.1007/s12013-011-9193-5
139
Laura Guarnaccia, Giovanni Marfia, Matteo Maria Masseroli, Stefania Elena Navone, Melissa Balsamo, Manuela Caroli, Silvia Valtorta, Rosa Maria Moresco, Rolando Campanella, Emanuele Garzia, Laura Riboni, Marco Locatelli. Frontiers in Anti-Cancer Drug Discovery: Challenges and Perspectives of Metformin as Anti-Angiogenic Add-On Therapy in GlioblastomaCancers 2021; 14(1): 112 doi: 10.3390/cancers14010112
140
A. SCHERZED, S. HACKENBERG, K. FROELICH, K. RAK, P. SCHENDZIELORZ, T. GEHRKE, R. HAGEN, N. KLEINSASSER. The differentiation of hMSCs counteracts their migration capability and pro-angiogenic effects in vitroOncology Reports 2016; 35(1): 219 doi: 10.3892/or.2015.4383
141
Ran An, Rafael Schmid, Anne Klausing, Jan W. Robering, Maximilian Weber, Tobias Bäuerle, Rainer Detsch, Aldo R. Boccaccini, Raymund E. Horch, Anja M. Boos, Annika Weigand. Proangiogenic effects of tumor cells on endothelial progenitor cells vary with tumor type in an in vitro and in vivo rat model The FASEB Journal 2018; 32(10): 5587 doi: 10.1096/fj.201800135RR
142
T. A. Bhat, D. Nambiar, A. Pal, R. Agarwal, R. P. Singh. Fisetin inhibits various attributes of angiogenesis in vitro and in vivo--implications for angiopreventionCarcinogenesis 2012; 33(2): 385 doi: 10.1093/carcin/bgr282
143
Domenico Vitolo, Luciano Ciocci, Gloria Deriu, Silvia Spinelli, Stefania Cortese, Laura Masuelli, Stefania Morrone, Mary Jo Filice, Giorgio Furio Coloni, Pier Giorgio Natali, Carlo Davide Baroni. Laminin α2 Chain-Positive Vessels and Epidermal Growth Factor in Lung Neuroendocrine CarcinomaThe American Journal of Pathology 2006; 168(3): 991 doi: 10.2353/ajpath.2006.041310
144
Ji-Yu Li, Zhi-Wei Quan, Qiang Zhang, Jian-Wen Liu. The synergistic inhibitory effect of somatostatin-doxorubicin co-treatment on gallbladder carcinomaBMC Cancer 2007; 7(1) doi: 10.1186/1471-2407-7-125
145
Yan-Hao Huang, Jeon-Hor Chen, Yeun-Chung Chang, Chiun-Sheng Huang, Woo Kyung Moon, Wen-Jia Kuo, Kuan-Ju Lai, Ruey-Feng Chang. Diagnosis of Solid Breast Tumors Using Vessel Analysis in Three-Dimensional Power Doppler Ultrasound ImagesJournal of Digital Imaging 2013; 26(4): 731 doi: 10.1007/s10278-012-9556-5
146
Aeyung Kim, Jin Yeul Ma. Piceatannol-3-O-β-D-glucopyranoside (PG) exhibits in vitro anti-metastatic and anti-angiogenic activities in HT1080 malignant fibrosarcoma cellsPhytomedicine 2019; 57: 95 doi: 10.1016/j.phymed.2018.12.017
147
Yingzhuo Xu, Jian Wang, Xu Wang, Xiaoshu Zhou, Jing Tang, Xiaohua Jie, Xijie Yang, Xinrui Rao, Yunhong Xu, Biyuan Xing, Zhenyu Li, Gang Wu. Targeting ADRB2 enhances sensitivity of non-small cell lung cancer to VEGFR2 tyrosine kinase inhibitorsCell Death Discovery 2022; 8(1) doi: 10.1038/s41420-022-00818-8
148
Yu-Bin Ji, Shi-Yong Gao, Hong-Rui Ji, Qi Kong, Xiu-Juan Zhang, Bao-Feng Yang. Anti-neoplastic efficacy of Haimiding on gastric carcinoma and its mechanismsWorld Journal of Gastroenterology 2004; 10(4): 484-490 doi: 10.3748/wjg.v10.i4.484
149
Laura Porcza, Claire Simms, Mridula Chopra. Honey and Cancer: Current Status and Future DirectionsDiseases 2016; 4(4): 30 doi: 10.3390/diseases4040030
150
Hui Hua, Yu Zhu, Yu-He Song. Ruscogenin suppressed the hepatocellular carcinoma metastasis via PI3K/Akt/mTOR signaling pathwayBiomedicine & Pharmacotherapy 2018; 101: 115 doi: 10.1016/j.biopha.2018.02.031
151
Han‐Qi Wang, Qi‐Wen Man, Fang‐Yi Huo, Xin Gao, Hao Lin, Su‐Ran Li, Jing Wang, Fu‐Chuan Su, Lulu Cai,, Yi Shi, Bing Liu,, Lin‐Lin Bu. STAT3 pathway in cancers: Past, present, and futureMedComm 2022; 3(2) doi: 10.1002/mco2.124
152
Tchawe Yvan Sinclair Ngaha, Angelina V. Zhilenkova, Freddy Elad Essogmo, Ikenna K. Uchendu, Moses Owoicho Abah, Lionel Tabola Fossa, Zaiana D. Sangadzhieva, Varvara D. Sanikovich, Alexander S. Rusanov, Yuliya N. Pirogova, Alexander Boroda, Alexander Rozhkov, Jean D. Kemfang Ngowa, Leonid N. Bagmet, Marina I. Sekacheva. Angiogenesis in Lung Cancer: Understanding the Roles of Growth FactorsCancers 2023; 15(18): 4648 doi: 10.3390/cancers15184648
153
Amir Hossein Norooznezhad, Kamran Mansouri. Endothelial cell dysfunction, coagulation, and angiogenesis in coronavirus disease 2019 (COVID-19)Microvascular Research 2021; 137: 104188 doi: 10.1016/j.mvr.2021.104188
154
Sung‐Po Hsu, Pei‐Yin Ho, Yu‐Chih Liang, Yuan‐Soon Ho, Wen‐Sen Lee. Involvement of the JNK activation in terbinafine‐induced p21 up‐regulation and DNA synthesis inhibition in human vascular endothelial cellsJournal of Cellular Biochemistry 2009; 108(4): 860 doi: 10.1002/jcb.22314
155
Sandra Gallach, Silvia Calabuig-Fariñas, Eloisa Jantus-Lewintre, Carlos Camps. MicroRNAs: Promising New Antiangiogenic Targets in CancerBioMed Research International 2014; 2014: 1 doi: 10.1155/2014/878450
156
Chenggui Wang, Zengjie Zhang, Tianzhen Xu, Yiting Lou, Qingqing Wang, Haiming Jin, Lilian Zhang, Yongzeng Feng, Huazi Xu, Cong Mao. Upregulating mTOR/ERK signaling with leonurine for promoting angiogenesis and tissue regeneration in a full-thickness cutaneous wound modelFood & Function 2018; 9(4): 2374 doi: 10.1039/C7FO01289F
157
Sangmin Jung, Hyeonsu Jo, Sujin Hyung, Noo Li Jeon. Microfluidics and Biosensors in Cancer ResearchAdvances in Experimental Medicine and Biology 2022; 1379: 231 doi: 10.1007/978-3-031-04039-9_9
158
Behnaz Lahooti, Racheal G. Akwii, Fatema Tuz Zahra, Md Sanaullah Sajib, Margarita Lamprou, Ahmed Alobaida, Michail S. Lionakis, George Mattheolabakis, Constantinos M. Mikelis. Targeting endothelial permeability in the EPR effectJournal of Controlled Release 2023; 361: 212 doi: 10.1016/j.jconrel.2023.07.039
159
Wamidh H. Talib, Sally Atawneh, Areen Nabil Shakhatreh, Ghyda’a Nabil Shakhatreh, Islam Subhi Rasheed aljarrah, Reem Ali Hamed, Doaa Adel banyyounes, Intisar Hadi Al-Yasari. Anticancer potential of garlic bioactive constituents: Allicin, Z-ajoene, and organosulfur compoundsPharmacia 2024; 71: 1 doi: 10.3897/pharmacia.71.e114556
160
Chandrasekaran Guruvayoorappan, Girija Kuttan. Amentoflavone Inhibits Experimental Tumor Metastasis Through a Regulatory Mechanism Involving MMP-2, MMP-9, Prolyl Hydroxylase, Lysyl Oxidase, VEGF, ERK-1, ERK-2, STAT-1, nm23 and Cytokines in Lung Tissues of C57BL/6 MiceImmunopharmacology and Immunotoxicology 2008; 30(4): 711 doi: 10.1080/08923970802278276
161
Saeed Ataei Kachooei, Roya Rahmani, Nasrin Zareh, Fatemeh Donyadideh, Saba Ataei Kachooei, Mohammad Nabiuni, Sajjad Yazdansetad. Down-regulation of TGF-β, VEGF, and bFGF in vascular endothelial cells of chicken induced by a brittle star (Ophiocoma erinaceus) extractHeliyon 2020; 6(1): e03199 doi: 10.1016/j.heliyon.2020.e03199
162
Xiaoyu Dong, Zili He, Guangheng Xiang, Leyi Cai, Zhenjiang Xu, Cong Mao, Yongzeng Feng. Retracted: Paeoniflorin promotes angiogenesis and tissue regeneration in a full‐thickness cutaneous wound model through the PI3K/AKT pathwayJournal of Cellular Physiology 2020; 235(12): 9933 doi: 10.1002/jcp.29808
163
Shu-Yi Sun, Huanxin Zhang, Wei Fang, Xindong Chen, Bo Li, Xi-Qiao Feng. Advances in Applied Mechanics 2022; 55: 309 doi: 10.1016/bs.aams.2022.05.004
164
Manoj Kumar, Zheng-Ren Liu, Laxmi Thapa, Qing Chang, Da-Yu Wang, Ren-Yi Qin. Antiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line: Inhibition of vascular endothelial growth factor and matrix metalloproteinase-2 expression <i>in vitro</i>World Journal of Gastroenterology 2004; 10(3): 393-399 doi: 10.3748/wjg.v10.i3.393
165
Mehmet A. Kisacam. Nobiletin is capable of regulating certain anti-cancer pathways in a colon cancer cell lineNaunyn-Schmiedeberg's Archives of Pharmacology 2023; 396(3): 547 doi: 10.1007/s00210-022-02354-9
166
Anjana Soman, S. Asha Nair. Unfolding the cascade of SERPINA3: Inflammation to cancerBiochimica et Biophysica Acta (BBA) - Reviews on Cancer 2022; 1877(5): 188760 doi: 10.1016/j.bbcan.2022.188760
167
Mehtap Cevik, Esat Namal, Nur Dinc-Sener, Ulkuhan Iner-Koksal, Cavlan Ciftci, Belgin Susleyici. Investigation of Vascular Endothelial Growth Factor Polymorphisms on Risk, Metastasis, Laterality, and Prognosis of Colorectal Cancer in Turkish SubjectsGenetic Testing and Molecular Biomarkers 2022; 26(5): 298 doi: 10.1089/gtmb.2021.0213
168
Lin Chen, Tao Li, Rong Li, Bo Wei, Zheng Peng. Alphastatin downregulates vascular endothelial cells sphingosine kinase activity and suppresses tumor growth in nude mice bearing human gastric cancer xenograftsWorld Journal of Gastroenterology 2006; 12(26): 4130-4136 doi: 10.3748/wjg.v12.i26.4130
169
M. Wartenberg, F. Dönmez, P. Budde, H. Sauer. Stem CellsHandbook of Experimental Pharmacology 2006; 174: 53 doi: 10.1007/3-540-31265-X_3
170
XinYing Wu, JingFeng Zhang, BingYing Lin, MinMing Zhang. Molecular imaging of tumor angiogenesis using RGD-labeled iron oxide nanoparticlesChinese Science Bulletin 2010; 55(24): 2662 doi: 10.1007/s11434-010-4004-8
171
Péter Hamar. Local Production of Acute Phase Proteins: A Defense Reaction of Cancer Cells to Injury with Focus on FibrinogenInternational Journal of Molecular Sciences 2024; 25(6): 3435 doi: 10.3390/ijms25063435
172
Scott M. Haake, Brenda L. Rios, Ambra Pozzi, Roy Zent. Integrating integrins with the hallmarks of cancerMatrix Biology 2024;  doi: 10.1016/j.matbio.2024.04.003
173
Chandrabose Selvaraj, Umesh Panwar, Karthik Raja Ramalingam, Rajendran Vijayakumar, Sanjeev Kumar Singh. Secretory ProteinsAdvances in Protein Chemistry and Structural Biology 2023; 133: 55 doi: 10.1016/bs.apcsb.2022.10.003
174
Kattika Kaarj, Marianne Madias, Patarajarin Akarapipad, Soohee Cho, Jeong-Yeol Yoon. Paper-based in vitro tissue chip for delivering programmed mechanical stimuli of local compression and shear flowJournal of Biological Engineering 2020; 14(1) doi: 10.1186/s13036-020-00242-5
175
Saleh A. Almatroodi, Mansoor Ali Syed, Arshad Husain Rahmani. Potential Therapeutic Targets of Curcumin, Most Abundant Active Compound of Turmeric Spice: Role in the Management of Various Types of CancerRecent Patents on Anti-Cancer Drug Discovery 2021; 16(1): 3 doi: 10.2174/1574892815999201102214602
176
Wen Li, Fang Li, Yang Zhang, Hongtao Ren, Xing Bao, Zhongwei Wang, Yali Wang. X-Linked Inhibitor of Apoptosis Protein (XIAP)-Loaded Magnetic Mesoporous Silica Nanoparticles Incorporated with miR-233 to Improve Radio Sensitization of Cervical Cancer Cells and Promote ApoptosisJournal of Biomedical Nanotechnology 2022; 18(3): 747 doi: 10.1166/jbn.2022.3281
177
Khaled Farid, Hatem Elalfy, Salwa M. Abo El-khair, Hoda Elgamal, Tarek Besheer, Ali Elmokadem, Walaa Shabana, Sally Abed, Mohamed Elegezy, Ahmed Abd El-khalek, Ahmed El-Morsy, Amr Negm, Ayman Z. Elsamanoudy, Basem El deek, Talal Amer, Mahmoud El-Bendary. Prognostic value of vascular endothelial growth factor in both conventional and drug eluting beads transarterial chemoembolization for treatment of unresectable hepatocellular carcinoma in HCV patientsExpert Review of Gastroenterology & Hepatology 2020; 14(12): 1203 doi: 10.1080/17474124.2020.1823215
178
Wei-Wen Hu, Cheng-Hsien Lin, Zhen-Jie Hong. The enrichment of cancer stem cells using composite alginate/polycaprolactone nanofibersCarbohydrate Polymers 2019; 206: 70 doi: 10.1016/j.carbpol.2018.10.087
179
Franck Zinzindohoué, Thierry Lecomte, Pierre Laurent-Puig. Métalloprotéases de la matrice extracellulaire et cancers du tractus digestifGastroentérologie Clinique et Biologique 2005; 29(4): 434 doi: 10.1016/S0399-8320(05)80799-7
180
A. Prabhakara Rao, Neeraj Bokde, Saugata Sinha. Photoacoustic Imaging for Management of Breast Cancer: A Literature Review and Future PerspectivesApplied Sciences 2020; 10(3): 767 doi: 10.3390/app10030767
181
Costin Vlad Anastasiu, Marius Alexandru Moga, Andrea Elena Neculau, Andreea Bălan, Ioan Scârneciu, Roxana Maria Dragomir, Ana-Maria Dull, Liana-Maria Chicea. Biomarkers for the Noninvasive Diagnosis of Endometriosis: State of the Art and Future PerspectivesInternational Journal of Molecular Sciences 2020; 21(5): 1750 doi: 10.3390/ijms21051750
182
Aeyung Kim, Jin Yeul Ma. Rhaponticin decreases the metastatic and angiogenic abilities of cancer cells via suppression of the HIF‑1α pathwayInternational Journal of Oncology 2018;  doi: 10.3892/ijo.2018.4479
183
Oana Baru, Andreea Nutu, Cornelia Braicu, Cosmin Andrei Cismaru, Ioana Berindan-Neagoe, Smaranda Buduru, Mîndra Badea. Angiogenesis in Regenerative Dentistry: Are We Far Enough for Therapy?International Journal of Molecular Sciences 2021; 22(2): 929 doi: 10.3390/ijms22020929
184
Hamid A. Bakshi, Gerry A. Quinn, Mohamed M. Nasef, Vijay Mishra, Alaa A. A. Aljabali, Mohamed El-Tanani, Ángel Serrano-Aroca, Mateus Webba Da Silva, Paul A. McCarron, Murtaza M. Tambuwala. Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF PathwaysCells 2022; 11(9): 1502 doi: 10.3390/cells11091502
185
Jovana V. Jovankić, Danijela D. Nikodijević, Milena G. Milutinović, Aleksandra G. Nikezić, Vesna V. Kojić, Aleksandar M. Cvetković, Danijela M. Cvetković. Potential of Orlistat to induce apoptotic and antiangiogenic effects as well as inhibition of fatty acid synthesis in breast cancer cellsEuropean Journal of Pharmacology 2023; 939: 175456 doi: 10.1016/j.ejphar.2022.175456
186
Shuang-Jia Wang, Bei Sun, Zhuo-Xin Cheng, Hao-Xin Zhou, Yue Gao, Rui Kong, Hua Chen, Hong-Chi Jiang, Shang-Ha Pan, Dong-Bo Xue, Xue-Wei Bai. Dihydroartemisinin inhibits angiogenesis in pancreatic cancer by targeting the NF-κB pathwayCancer Chemotherapy and Pharmacology 2011; 68(6): 1421 doi: 10.1007/s00280-011-1643-7
187
Grit Kasper, Niels Dankert, Jens Tuischer, Moritz Hoeft, Timo Gaber, Juliane D. Glaeser, Desiree Zander, Miriam Tschirschmann, Mark Thompson, Georg Matziolis, Georg N. Duda. Mesenchymal Stem Cells Regulate Angiogenesis According to Their Mechanical EnvironmentStem Cells 2007; 25(4): 903 doi: 10.1634/stemcells.2006-0432
188
Cho-Won Kim, Hong Kyu Lee, Min-Woo Nam, Gabsang Lee, Kyung-Chul Choi. The role of KiSS1 gene on the growth and migration of prostate cancer and the underlying molecular mechanismsLife Sciences 2022; 310: 121009 doi: 10.1016/j.lfs.2022.121009
189
Maryam Ateeq, Mark Broadwin, Frank W. Sellke, M. Ruhul Abid. Extracellular Vesicles’ Role in Angiogenesis and Altering Angiogenic SignalingMedical Sciences 2024; 12(1): 4 doi: 10.3390/medsci12010004
190
Renata T Paiva, Alessandra M Saliba, Tatiana O Fulco, Jorgenilce de Souza Sales, Daniel Serra de Carvalho, Elizabeth P Sampaio, Ulisses G Lopes, Euzenir N Sarno, Flavio F Nobre. A framework to identify gene expression profiles in a model of inflammation induced by lipopolysaccharide after treatment with thalidomideBMC Research Notes 2012; 5(1) doi: 10.1186/1756-0500-5-292
191
Ke Guo, Jie Li, Haihe Wang, Motomi Osato, Jing Ping Tang, Samantha Yiling Quah, Bin Qi Gan, Qi Zeng. PRL-3 Initiates Tumor Angiogenesis by Recruiting Endothelial Cells In vitro and In vivo Cancer Research 2006; 66(19): 9625 doi: 10.1158/0008-5472.CAN-06-0726
192
Nora A Mohamad, Graciela P Cricco, Lorena A Sambuco, M&aacute;ximo Croci, Vanina A Medina, Alicia S Guti&eacute;rrez, Rosa M Bergoc, Elena S Rivera, Gabriela A Mart&iacute;n. Aminoguanidine impedes human pancreatic tumor growth and metastasis development in nude miceWorld Journal of Gastroenterology 2009; 15(9): 1065-1071 doi: 10.3748/wjg.15.1065
193
A. F. Costa, A. P. D. Demasi, V. L. L. Bonfitto, J. F. L. Bonfitto, C. Furuse, V. C. Araújo, K. Metze, A. Altemani. Angiogenesis in salivary carcinomas with and without myoepithelial differentiationVirchows Archiv 2008; 453(4): 359 doi: 10.1007/s00428-008-0664-z
194
Elvan Caglar Citak, Aynur Oguz, Ceyda Karadeniz, Nalan Akyurek. Immunohistochemical expression of angiogenic cytokines in childhood Hodgkin lymphomaPathology - Research and Practice 2008; 204(2): 89 doi: 10.1016/j.prp.2007.11.005
195
Elvan Caglar Citak, Aynur Oguz, Ceyda Karadeniz, Nalan Akyurek. ROLE OF GELATINASES (MMP-2 AND MMP-9), TIMP-1, VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF), AND MICROVESSEL DENSITY ON THE CLINICOPATHOLOGICAL BEHAVIOR OF CHILDHOOD NON-HODGKIN LYMPHOMAPediatric Hematology and Oncology 2008; 25(1): 55 doi: 10.1080/08880010701826866
196
Mary Ann Stevenson, Stuart K. Calderwood. Clinical Radiation Oncology2016; : 41 doi: 10.1016/B978-0-323-24098-7.00002-2
197
Monica SM Chan, Shi-Fan Chen, Saulo JA Felizola, Lin Wang, Noriko Nemoto, Kentaro Tamaki, Takanori Ishida, Louis W.C. Chow, Noriaki Ohuchi, Hironobu Sasano. Correlation of Tumor-Infiltrative Lymphocyte Subtypes Alteration with Neoangiogenesis before and after Neoadjuvant Chemotherapy Treatment in Breast Cancer PatientsThe International Journal of Biological Markers 2014; 29(3): 193 doi: 10.5301/jbm.5000082
198
Tong‐Sheng Lee, Jhen‐Jhe Lin, Yen‐Nien Huo, Wen‐Sen Lee. Progesterone Inhibits Endothelial Cell Migration Through Suppression of the Rho Activity Mediated by cSrc ActivationJournal of Cellular Biochemistry 2015; 116(7): 1411 doi: 10.1002/jcb.25101
199
Ranjitha Gopalappa, Poornima D. Vijendra, Pratap G. Kenchappa, Kumar Vadlapudi. Natural Products as Cancer TherapeuticsAdvances in Medical Diagnosis, Treatment, and Care 2023; : 106 doi: 10.4018/979-8-3693-0703-8.ch005
200
Yu-Tang Tung, Pin-Wu Huang, Yu-Ching Chou, Cheng-Wei Lai, Hsiu-Po Wang, Heng-Chien Ho, Chih-Ching Yen, Chih-Yen Tu, Tung-Chou Tsai, Dah-Cherng Yeh, Jiun-Long Wang, Kowit-Yu Chong, Chuan-Mu Chen. Lung tumorigenesis induced by human vascular endothelial growth factor (hVEGF)-A165 overexpression in transgenic mice and amelioration of tumor formation by miR-16Oncotarget 2015; 6(12): 10222 doi: 10.18632/oncotarget.3390
201
Huanxin Zhang, Bo Li, Yue Shao, Xi-Qiao Feng. Morphomechanics of tumorsCurrent Opinion in Biomedical Engineering 2020; 15: 51 doi: 10.1016/j.cobme.2020.01.004
202
MENG-SHU TSAI, CHENG-CHI CHANG, MIN-LIANG KUO, YING-TAI WU. Vascular endothelial growth factor-A and changes in a tumor-bearing mouse model with Lewis lung cancerOncology Letters 2011; 2(6): 1143 doi: 10.3892/ol.2011.380
203
Juana Virginia Tapia-Vieyra, Blanca Delgado-Coello, Jaime Mas-Oliva. Atherosclerosis and Cancer; A Resemblance with Far-reaching ImplicationsArchives of Medical Research 2017; 48(1): 12 doi: 10.1016/j.arcmed.2017.03.005
204
Tetsuya Nomura, Keiichi Hirata, Takuto Shimaoka, Makie Yamakawa, Naoya Koizumi, Ryo Suzuki, Kazuo Maruyama, Naoki Utoguchi. Cancer Vaccine Therapy Using Tumor Endothelial Cells as Antigens Suppresses Solid Tumor Growth and MetastasisBiological & Pharmaceutical Bulletin 2017; 40(10): 1661 doi: 10.1248/bpb.b17-00145
205
F Kosova, FO Kurt, E Olmez, I Tuğlu, Z Arı. Effects of caffeic acid phenethyl ester on matrix molecules and angiogenetic and anti-angiogenetic factors in gastric cancer cells cultured on different substratesBiotechnic & Histochemistry 2016; 91(1): 38 doi: 10.3109/10520295.2015.1072769
206
De-Sheng Wang, Ke-Feng Dou, Kai-Zong Li, Zhen-Shun Song. Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathwayWorld Journal of Gastroenterology 2004; 10(2): 299-302 doi: 10.3748/wjg.v10.i2.299