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Cited by in CrossRef
For: Qin TJ, Zhao XH, Yun J, Zhang LX, Ruan ZP, Pan BR. Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma. World J Gastroenterol 2008; 14(33): 5210-5216 [PMID: 18777599 DOI: 10.3748/wjg.14.5210]
URL: https://www.wjgnet.com/1007-9327/full/v14/i33/5210.htm
Number Citing Articles
1
Yitao Gong, Zhiyao Fan, Guopei Luo, Chao Yang, Qiuyi Huang, Kun Fan, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Chen Liu. The role of necroptosis in cancer biology and therapyMolecular Cancer 2019; 18(1) doi: 10.1186/s12943-019-1029-8
2
Lina Ma, Bing Song, Hua Jin, Jiang Pi, Li Liu, Jinhuan Jiang, Jiye Cai. Cinobufacini induced MDA-MB-231 cell apoptosis-associated cell cycle arrest and cytoskeleton functionBioorganic & Medicinal Chemistry Letters 2012; 22(3): 1459 doi: 10.1016/j.bmcl.2011.11.095
3
Munehiro Nakata, Shota Kawaguchi, Ayami Oikawa, Akito Inamura, Shunki Nomoto, Hirokazu Miyai, Tomomi Nonaka, Saeko Ichimi, Yoko Fujita-Yamaguchi, Chuan Luo, Bo Gao, Wei Tang. An aqueous extract from toad skin prevents gelatinase activities derived from fetal serum albumin and serum-free culture medium of human breast carcinoma MDA-MB-231 cellsDrug Discoveries & Therapeutics 2015; 9(6): 417 doi: 10.5582/ddt.2015.01060
4
Xiaoling Song, Yunping Hu, Yongsheng Li, Rong Shao, Fatao Liu, Yingbin Liu. Overview of current targeted therapy in gallbladder cancerSignal Transduction and Targeted Therapy 2020; 5(1) doi: 10.1038/s41392-020-00324-2
5
Trapti Aggarwal, Akhilesh K. Verma. Protecting‐Group‐Free Organic Synthesis2018; : 133 doi: 10.1002/9781119295266.ch5
6
Qi Wu, Shao-Ping Wang, Xiao-Xue Sun, Yu-Fan Tao, Xiao-Qing Yuan, Qi-Mei Chen, Long Dai, Chun-Lei Li, Jia-Yu Zhang, Ai-Lin Yang. HuaChanSu suppresses tumor growth and interferes with glucose metabolism in hepatocellular carcinoma cells by restraining Hexokinase-2The International Journal of Biochemistry & Cell Biology 2022; 142: 106123 doi: 10.1016/j.biocel.2021.106123
7
Rui-Fang Xie, Zhi-Cheng Li, Pei-Pei Chen, Xin Zhou. Bufothionine induced the mitochondria-mediated apoptosis in H22 liver tumor and acute liver injuryChinese Medicine 2015; 10(1) doi: 10.1186/s13020-015-0033-1
8
Masami Ichikawa, Yoshihiro Sowa, Yosuke Iizumi, Yuichi Aono, Toshiyuki Sakai, Sumitra Deb. Resibufogenin Induces G1-Phase Arrest through the Proteasomal Degradation of Cyclin D1 in Human Malignant Tumor CellsPLOS ONE 2015; 10(6): e0129851 doi: 10.1371/journal.pone.0129851
9
Neha Yadav, Rohitas Deshmukh, Rupa Mazumder. A comprehensive review on the use of traditional Chinese medicine for cancer treatmentPharmacological Research - Modern Chinese Medicine 2024; 11: 100423 doi: 10.1016/j.prmcm.2024.100423
10
F. Meriggi, A. Zaniboni. Gemox: A Widely Useful Therapy Against Solid Tumors-Review and Personal ExperienceJournal of Chemotherapy 2010; 22(5): 298 doi: 10.1179/joc.2010.22.5.298
11
Yafeng Sun, Xianhong Zhang. RETRACTED: Bufothionine Promotes Apoptosis via Triggering ER Stress and Synergizes with Temozolomide in Glioblastoma Multiforme CellsThe Anatomical Record 2019; 302(11): 1950 doi: 10.1002/ar.24194
12
Yinfang Xu, Xuan Liu, Silvia Schwarz, Lihong Hu, Dean Guo, Quanbao Gu, Wolfgang Schwarz. Inhibitory efficacy of bufadienolides on Na + ,K + -pump activity versus cell proliferationBiochemistry and Biophysics Reports 2016; 6: 158 doi: 10.1016/j.bbrep.2016.03.015
13
Bo-Bo Zheng, Quan Wang, Yumin Yue, Jiang Li, Xiao-Jun Li, Xin Wang, Syed Sameer Aga. Network Pharmacology and Molecular Docking Validation to Reveal the Pharmacological Mechanisms of Kangai Injection against Colorectal CancerBioMed Research International 2022; 2022: 1 doi: 10.1155/2022/3008842
14
Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, Yasuhide Hibino, Mari Okazaki. Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87Molecules 2022; 27(19): 6577 doi: 10.3390/molecules27196577
15
Jinglin Zou, Cong Jiang, Xianglong Li, Tianyu Zhong, Shuqi Wang, Bo Wang, Dapeng Zhang, Ji-Na Hao, Yuanyuan Cao, Mengjia Guan, Peng Zhang, Bin Dai, Yongsheng Li. Redox-responsive engineered hybrid nanomedicine for gallbladder cancer therapy via hyaluronic acid depletionApplied Materials Today 2023; 30: 101707 doi: 10.1016/j.apmt.2022.101707
16
Chun Li, Saeed M. Hashimi, Siyu Cao, Ji Qi, David Good, Wei Duan, Ming Q. Wei. Chansu inhibits the expression of cortactin in colon cancer cell lines in vitro and in vivoBMC Complementary and Alternative Medicine 2015; 15(1) doi: 10.1186/s12906-015-0723-3
17
Li-Juan Deng, Yong Li, Ming Qi, Jun-Shan Liu, Sheng Wang, Li-Jun Hu, Yu-He Lei, Ren-Wang Jiang, Wei-Min Chen, Qi Qi, Hai-Yan Tian, Wei-Li Han, Bao-Jian Wu, Jia-Xu Chen, Wen-Cai Ye, Dong-Mei Zhang. Molecular mechanisms of bufadienolides and their novel strategies for cancer treatmentEuropean Journal of Pharmacology 2020; 887: 173379 doi: 10.1016/j.ejphar.2020.173379
18
Linxuan Miao, Ying Liu, Nasra Mohamoud Ali, Yan Dong, Bin Zhang, Xiaonan Cui. Bufalin serves as a pharmaceutic that mitigates drug resistanceDrug Metabolism Reviews 2023; 55(3): 195 doi: 10.1080/03602532.2023.2206065
19
Fanghua Qi, Anyuan Li, Yoshinori Inagaki, Norihiro Kokudo, Sumihito Tamura, Munehiro Nakata, Wei Tang. Antitumor activity of extracts and compounds from the skin of the toad Bufo bufo gargarizans CantorInternational Immunopharmacology 2011; 11(3): 342 doi: 10.1016/j.intimp.2010.12.007
20
Jingnan Xu, Zhuo Song, Qiujun Guo, Jie Li. Synergistic Effect and Molecular Mechanisms of Traditional Chinese Medicine on Regulating Tumor Microenvironment and Cancer CellsBioMed Research International 2016; 2016: 1 doi: 10.1155/2016/1490738
21
Dong-yan Chen, Rui Zhang, Ying Liu, Tao Zhou, Xiang Li, Shan Gao, Jian Zhang, Xiao-nan Cui. Effects of cinobufacini injection on hepatocarcinoma cell proliferation, invasion and metastasisRSC Advances 2016; 6(85): 82417 doi: 10.1039/C6RA08923B
22
Jinnong Li, Zhenhua Liu, Ruiqi Chen, Dan Hu, Wenjuan Li, Xiajing Li, Xuzheng Chen, Baokang Huang, Lianming Liao. The quality of reports of randomized clinical trials on traditional Chinese medicine treatments: a systematic review of articles indexed in the China National Knowledge Infrastructure database from 2005 to 2012BMC Complementary and Alternative Medicine 2014; 14(1) doi: 10.1186/1472-6882-14-362
23
Lingyu Han, Bo Yuan, Ryota Shimada, Hideki Hayashi, Nan Si, Hai-Yu Zhao, Baolin Bian, Norio Takagi. Cytocidal effects of arenobufagin and hellebrigenin, two active bufadienolide compounds, against human glioblastoma cell line U-87International Journal of Oncology 2018;  doi: 10.3892/ijo.2018.4567
24
Guangxin Zhang, Chao Wang, Mei Sun, Jindong Li, Bin Wang, Chengyan Jin, Peiyan Hua, Ge Song, Yifan Zhang, Lisa L.H. Nguyen, Ranji Cui, Runhua Liu, Lizhong Wang, Xingyi Zhang. Cinobufagin inhibits tumor growth by inducing intrinsic apoptosis through AKT signaling pathway in human nonsmall cell lung cancer cellsOncotarget 2016; 7(20): 28935 doi: 10.18632/oncotarget.7898
25
Karla de Castro Figueiredo Bordon, Camila Takeno Cologna, Elisa Corrêa Fornari-Baldo, Ernesto Lopes Pinheiro-Júnior, Felipe Augusto Cerni, Fernanda Gobbi Amorim, Fernando Antonio Pino Anjolette, Francielle Almeida Cordeiro, Gisele Adriano Wiezel, Iara Aimê Cardoso, Isabela Gobbo Ferreira, Isadora Sousa de Oliveira, Johara Boldrini-França, Manuela Berto Pucca, Mateus Amaral Baldo, Eliane Candiani Arantes. From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug DiscoveryFrontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.01132
26
Jie Wang, Han Cai, Qiaoli Liu, Yue Xia, LiKai Xing, Qingsong Zuo, Yong Zhang, Cao Chen, Ke Xu, Peihao Yin, Teng Chen. Cinobufacini Inhibits Colon Cancer Invasion and Metastasis via Suppressing Wnt/β-Catenin Signaling Pathway and EMTThe American Journal of Chinese Medicine 2020; 48(03): 703 doi: 10.1142/S0192415X20500354
27
Qing Wu, Wei-Dong Lin, Guan-Qun Liao, Li-Guo Zhang, Shun-Qian Wen, Jia-Ying Lin. Antiproliferative effects of cinobufacini on human hepatocellular carcinoma HepG2 cells detected by atomic force microscopyWorld Journal of Gastroenterology 2015; 21(3): 854-861 doi: 10.3748/wjg.v21.i3.854
28
Yue Hao, Xinxin Luo, Xiyuan Ba, Jiali Wang, Shiyang Zhou, Shimin Yang, Changji Fang, Changyu Jiang, Wuping Sun. Huachansu suppresses TRPV1 up-regulation and spinal astrocyte activation to prevent oxaliplatin-induced peripheral neuropathic pain in ratsGene 2019; 680: 43 doi: 10.1016/j.gene.2018.09.035
29
Dong-Ze Qiu, Zhou-Ji Zhang, Wei-Zhong Wu, Yun-Ke Yang. Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cellsBMC Complementary and Alternative Medicine 2013; 13(1) doi: 10.1186/1472-6882-13-185
30
Bo Yuan, Ryota Shimada, Kang Xu, Lingyu Han, Nan Si, Haiyu Zhao, Baolin Bian, Hideki Hayashi, Mari Okazaki, Norio Takagi. Multiple cytotoxic effects of gamabufotalin against human glioblastoma cell line U-87Chemico-Biological Interactions 2019; 314: 108849 doi: 10.1016/j.cbi.2019.108849
31
Fanghua Qi, Lin Zhao, Aiyan Zhou, Bo Zhang, Anyuan Li, Zhixue Wang, Junqing Han. The advantages of using traditional Chinese medicine as an adjunctive therapy in the whole course of cancer treatment instead of only terminal stage of cancerBioScience Trends 2015; 9(1): 16 doi: 10.5582/bst.2015.01019
32
Konstantinos Alevizopoulos, Konstantinos Dimas, Natalia Papadopoulou, Eva-Maria Schmidt, Anna Tsapara, Saad Alkahtani, Sabina Honisch, Kyriakos C. Prousis, Saud Alarifi, Theodora Calogeropoulou, Florian Lang, Christos Stournaras. Functional characterization and anti-cancer action of the clinical phase II cardiac Na+/K+ ATPase inhibitor istaroxime: in vitro and in vivo properties and cross talk with the membrane androgen receptorOncotarget 2016; 7(17): 24415 doi: 10.18632/oncotarget.8329
33
Guojun Wang, Guanghui Liu, Yanwei Ye, Yang Fu, Xiefu Zhang. Bufothionine exerts anti-cancer activities in gastric cancer through Pim3Life Sciences 2019; 232: 116615 doi: 10.1016/j.lfs.2019.116615
34
Jihan Huang, Feiyu Chen, Zhangfeng Zhong, Hor Yue Tan, Ning Wang, Yuting Liu, Xinyuan Fang, Tao Yang, Yibin Feng. Interpreting the Pharmacological Mechanisms of Huachansu Capsules on Hepatocellular Carcinoma Through Combining Network Pharmacology and Experimental EvaluationFrontiers in Pharmacology 2020; 11 doi: 10.3389/fphar.2020.00414
35
Laura Soumoy, Ghanem E. Ghanem, Sven Saussez, Fabrice Journe. Bufalin for an innovative therapeutic approach against cancerPharmacological Research 2022; 184: 106442 doi: 10.1016/j.phrs.2022.106442
36
Jinhao Jia, Jie Li, Qiusheng Zheng, Defang Li. A research update on the antitumor effects of active components of Chinese medicine ChanSuFrontiers in Oncology 2022; 12 doi: 10.3389/fonc.2022.1014637
37
Elisa Correa Fornari Baldo, Fernando Antonio Pino Anjolette, Eliane Candiani Arantes, Mateus Amaral Baldo. Toxins and Drug Discovery2015; : 1 doi: 10.1007/978-94-007-6726-3_16-1
38
Mohammad Ali, Shahid Ud Din Wani, Md Salahuddin, Manjula S.N., Mruthunjaya K, Tathagata Dey, Mohammed Iqbal Zargar, Jagadeesh Singh. Recent advance of herbal medicines in cancer- a molecular approachHeliyon 2023; 9(2): e13684 doi: 10.1016/j.heliyon.2023.e13684
39
Current awareness: Pharmacoepidemiology and drug safetyPharmacoepidemiology and Drug Safety 2009; 18(2) doi: 10.1002/pds.1645
40
Chun Li, Saeed M. Hashimi, Siyu Cao, Albert S. Mellick, Wei Duan, David Good, Ming Q. Wei. The Mechanisms of Chansu in Inducing Efficient Apoptosis in Colon Cancer CellsEvidence-Based Complementary and Alternative Medicine 2013; 2013: 1 doi: 10.1155/2013/849054
41
Kaili Wang, Danxia Chu, Jie Wu, Mengling Zhao, Miaomiao Zhang, Bijun Li, Wenjun Du, Jianmin Du, Ruixia Guo. WITHDRAWN: Cinobufagin induced cell apoptosis and protective autophagy through the ROS/MAPK signaling pathwayLife Sciences 2019; : 116642 doi: 10.1016/j.lfs.2019.116642
42
Bo Yuan, Jing He, Keishi Kisoh, Hideki Hayashi, Sachiko Tanaka, Nan Si, Hai-Yu Zhao, Toshihiko Hirano, Baolin Bian, Norio Takagi. Effects of active bufadienolide compounds on human cancer cells and CD4+CD25+Foxp3+ regulatory T cells in mitogen-activated human peripheral blood mononuclear cellsOncology Reports 2016; 36(3): 1377 doi: 10.3892/or.2016.4946
43
Cameron T. Durlacher, Kevin Chow, Xiao‐Wu Chen, Zhi‐Xu He, Xueji Zhang, Tianxin Yang, Shu‐Feng Zhou. Targeting Na+/K+‐translocating adenosine triphosphatase in cancer treatmentClinical and Experimental Pharmacology and Physiology 2015; 42(5): 427 doi: 10.1111/1440-1681.12385
44
Xiyuan Ba, Jiali Wang, Shiyang Zhou, Xinxin Luo, Yun Peng, Shimin Yang, Yue Hao, Guangyi Jin. Cinobufacini protects against paclitaxel-induced peripheral neuropathic pain and suppresses TRPV1 up-regulation and spinal astrocyte activation in ratsBiomedicine & Pharmacotherapy 2018; 108: 76 doi: 10.1016/j.biopha.2018.09.018
45
Kevin Yi-Lwern Yap, Ken Juin Lim. Merging the old with the new: a cybermedicine marriage for oncology interactions with traditional herbal therapies and complementary medicinesTANG [HUMANITAS MEDICINE] 2012; 2(2): 18.1 doi: 10.5667/tang.2012.0004
46
Maen Zeino, Malte S. Paulsen, Martin Zehl, Ernst Urban, Brigitte Kopp, Thomas Efferth. Identification of new P-glycoprotein inhibitors derived from cardiotonic steroidsBiochemical Pharmacology 2015; 93(1): 11 doi: 10.1016/j.bcp.2014.10.009
47
Zhili Shen, Yan Li, Chengcheng Zhao, Fen Wang, Rongping Zhou, Gang Chen. miR‑494‑BAG‑1 axis is involved in cinobufacini‑induced cell proliferation and apoptosis in gastric cancerMolecular Medicine Reports 2018;  doi: 10.3892/mmr.2018.8788
48
David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, James R. Miller, Stanley P. Leong, Kevin B. Kim, Wilson Liao, Liliana Soroceanu, Sean McAllister, Robert J. Debs, Dirk Schadendorf, Sancy A. Leachman, James E. Cleaver, Mohammed Kashani-Sabet. Nuclear Receptor Coactivator NCOA3 Regulates UV Radiation–Induced DNA Damage and Melanoma SusceptibilityCancer Research 2021; 81(11): 2956 doi: 10.1158/0008-5472.CAN-20-3450
49
Jiao CHEN, Dan LIN, Jie YANG, XueTing CAI, GuoLi WEI, Peng CAO. Advances in the synergistic and toxic attenuating effect of traditional Chinese medicine in cancer treatmentSCIENTIA SINICA Vitae 2022; 52(6): 920 doi: 10.1360/SSV-2021-0389
50
Li-Juan Deng, Yu-He Lei, Jing-Yu Quan, Bao-Jing Li, Dong-Mei Zhang, Hai-Yan Tian, Ye Chen, En-Xin Zhang, Lei Chen, Wen-Cai Ye, Wei-Min Ning, Lin-Zhong Yu, Jun-Shan Liu. 1β–OH–arenobufagin induces mitochondrial apoptosis in hepatocellular carcinoma through the suppression of mTOR signaling pathwayJournal of Ethnopharmacology 2021; 266: 113443 doi: 10.1016/j.jep.2020.113443
51
Chien-shan Cheng, Jiaqiang Wang, Jie Chen, Kuei Ting Kuo, Jian Tang, Huifeng Gao, Lianyu Chen, Zhen Chen, Zhiqiang Meng. New therapeutic aspects of steroidal cardiac glycosides: the anticancer properties of Huachansu and its main active constituent BufalinCancer Cell International 2019; 19(1) doi: 10.1186/s12935-019-0806-1
52
Lu Kong, Xu Liu, Bing Yu, Ye Yuan, Qianru Zhao, Yuru Chen, Bin Qu, Xue Du, Xiaoxuan Tian, Rui Shao, Yu Wang. Cinobufacini Injection Inhibits the Proliferation of Triple-Negative Breast Cancer Through the Pin1–TAZ Signaling PathwayFrontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.797873
53
Munehiro Nakata, Shuya Mori, Yo Kamoshida, Shota Kawaguchi, Yoko Fujita-Yamaguchi, Bo Gao, Wei Tang. Toad skin extract cinobufatini inhibits migration of human breast carcinoma MDA-MB-231 cells into a model stromal tissueBioScience Trends 2015; 9(4): 266 doi: 10.5582/bst.2015.01109
54
Qingxi Yue, Hong Zhen, Ming Huang, Xi Zheng, Lixing Feng, Baohong Jiang, Min Yang, Wanying Wu, Xuan Liu, Dean Guo, Luis Eduardo M Quintas. Proteasome Inhibition Contributed to the Cytotoxicity of Arenobufagin after Its Binding with Na, K-ATPase in Human Cervical Carcinoma HeLa CellsPLOS ONE 2016; 11(7): e0159034 doi: 10.1371/journal.pone.0159034
55
Qian Li, Chuanwu Jiang, Yan Wang, Minghua Wei, Huijin Zheng, Yanqi Xu, Xuegang Xu, Fengyu Jia, Kai Liu, Gang Sun, Jianhua Zang, Ping Mo. RETRACTED ARTICLE: Resibufogenin suppresses tumor growth and inhibits glycolysis in ovarian cancer by modulating PIM1Naunyn-Schmiedeberg's Archives of Pharmacology 2019; 392(12): 1477 doi: 10.1007/s00210-019-01687-2
56
Rui-Fang Xie, Zhi-Cheng Li, Bo Gao, Zhi-Na Shi, Xin Zhou. Bufothionine, a possible effective component in cinobufocini injection for hepatocellular carcinomaJournal of Ethnopharmacology 2012; 141(2): 692 doi: 10.1016/j.jep.2011.12.018
57
Shu-Yi Yin, Wen-Chi Wei, Feng-Yin Jian, Ning-Sun Yang. Therapeutic Applications of Herbal Medicines for Cancer PatientsEvidence-Based Complementary and Alternative Medicine 2013; 2013: 1 doi: 10.1155/2013/302426
58
Elisa Correa Fornari Baldo, Fernando Antonio Pino Anjolette, Eliane Candiani Arantes, Mateus Amaral Baldo. Toxins and Drug DiscoveryToxinology 2017; : 373 doi: 10.1007/978-94-007-6452-1_16
59
Alexander A. Azizi, Angela Lamarca, Mairéad G. McNamara, Juan W. Valle. Chemotherapy for advanced gallbladder cancer (GBC): A systematic review and meta-analysisCritical Reviews in Oncology/Hematology 2021; 163: 103328 doi: 10.1016/j.critrevonc.2021.103328
60
EKEM T. EFUET, XIAO-PING DING, CARRIE CARTWRIGHT, YONG PAN, LORENZO COHEN, PEIYING YANG. Huachansu mediates cell death in non-Hodgkin’s lymphoma by induction of caspase-3 and inhibition of MAP kinaseInternational Journal of Oncology 2015; 47(2): 592 doi: 10.3892/ijo.2015.3044
61
Jie Wang, Chao Chen, Shiying Wang, Yong Zhang, Peihao Yin, Zhongxiang Gao, Jie Xu, Dianxu Feng, Qinsong Zuo, Ronghua Zhao, Teng Chen. Bufalin Inhibits HCT116 Colon Cancer Cells and Its Orthotopic Xenograft Tumor in Mice Model through Genes Related to Apoptotic and PTEN/AKT PathwaysGastroenterology Research and Practice 2015; 2015: 1 doi: 10.1155/2015/457193
62
Li-Juan Deng, Long-Hai Wang, Cheng-Kang Peng, Yi-Bin Li, Mao-Hua Huang, Min-Feng Chen, Xue-Ping Lei, Ming Qi, Yun Cen, Wen-Cai Ye, Dong-Mei Zhang, Wei-Min Chen. Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced CardiotoxicityJournal of Medicinal Chemistry 2017; 60(13): 5320 doi: 10.1021/acs.jmedchem.6b01755
63
Jufeng Xia, Yoshinori Inagaki, Jianjun Gao, Fanghua Qi, Peipei Song, Guohua Han, Tatsuo Sawakami, Bo Gao, Chuan Luo, Norihiro Kokudo, Kiyoshi Hasegawa, Yoshihiro Sakamoto, Wei Tang. Combination of Cinobufacini and Doxorubicin Increases Apoptosis of Hepatocellular Carcinoma Cells through the Fas- and Mitochondria-Mediated PathwaysThe American Journal of Chinese Medicine 2017; 45(07): 1537 doi: 10.1142/S0192415X17500835
64
Jian-Hua Yin, Xiao-Yan Zhu, Wei-Dong Shi, Lu-Ming Liu. Huachansu injection inhibits metastasis of pancreatic cancer in mice model of human tumor xenograftBMC Complementary and Alternative Medicine 2014; 14(1) doi: 10.1186/1472-6882-14-483
65
Xiaolu Wei, Nan Si, Yuefei Zhang, Haiyu Zhao, Jian Yang, Hongjie Wang, Lianmei Wang, Linyu Han, Baolin Bian, Tao Lu. Evaluation of Bufadienolides as the Main Antitumor Components in Cinobufacin Injection for Liver and Gastric Cancer TherapyPLOS ONE 2017; 12(1): e0169141 doi: 10.1371/journal.pone.0169141
66
Yinglu Feng, Yongan Chen, Yongbin Meng, Qingxin Cao, Qun Liu, Changquan Ling, Chen Wang. Bufalin Suppresses Migration and Invasion of Hepatocellular Carcinoma Cells Elicited by Poly (I:C) TherapyOncoImmunology 2018; 7(5): e1426434 doi: 10.1080/2162402X.2018.1426434
67
Xiao Sun, Tony T.H. Ng, Kathy W.Y. Sham, Lin Zhang, Matthew T.V. Chan, William K.K. Wu, Christopher H.K. Cheng. Bufalin, a Traditional Chinese Medicine Compound, Prevents Tumor Formation in Two Murine Models of Colorectal CancerCancer Prevention Research 2019; 12(10): 653 doi: 10.1158/1940-6207.CAPR-19-0134
68
Jinghui Zhang, Yanjun Hong, Lilong Jiang, Xiaojiao Yi, Yang Chen, Li Liu, Zhongjian Chen, Yongjiang Wu, Zongwei Cai. Global Metabolomic and Lipidomic Analysis Reveal the Synergistic Effect of Bufalin in Combination with Cinobufagin against HepG2 CellsJournal of Proteome Research 2020; 19(2): 873 doi: 10.1021/acs.jproteome.9b00681
69
Fanghua Qi, Anyuan Li, Lin Zhao, Huanli Xu, Yoshinori Inagaki, Dongliang Wang, Xiaoyan Cui, Bo Gao, Norihiro Kokudo, Munehiro Nakata, Wei Tang. Cinobufacini, an aqueous extract from Bufo bufo gargarizans Cantor, induces apoptosis through a mitochondria-mediated pathway in human hepatocellular carcinoma cellsJournal of Ethnopharmacology 2010; 128(3): 654 doi: 10.1016/j.jep.2010.02.022
70
YING LIU, LI-YING BAN, XI SU, SHAN GAO, JI-WEI LIU, XIAO-NAN CUI. Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG-2 hepatocellular carcinoma cellsMolecular Medicine Reports 2015; 12(1): 1598 doi: 10.3892/mmr.2015.3552
71
Bo Yuan, Kang Xu, Ryota Shimada, JingZhe Li, Hideki Hayashi, Mari Okazaki, Norio Takagi. Cytotoxic Effects of Arsenite in Combination With Gamabufotalin Against Human Glioblastoma Cell LinesFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.628914
72
Ying Long, Jialong Fan, Naduo Zhou, Jiahao Liang, Chang Xiao, Chunyi Tong, Wei Wang, Bin Liu. Biomimetic Prussian blue nanocomplexes for chemo-photothermal treatment of triple-negative breast cancer by enhancing ICDBiomaterials 2023; 303: 122369 doi: 10.1016/j.biomaterials.2023.122369
73
Ruhi Dixit, Manoj Pandey, Punam Pandey, V. K. Shukla. Bioeconomy for Sustainable Development2020; : 379 doi: 10.1007/978-981-13-9431-7_20
74
Emma K. Davison, Jonathan Sperry. Alkaloids from the traditional chinese medicine ChanSu: synthesis-enabled structural reassignment of bufopyramide to bufoserotonin COrganic & Biomolecular Chemistry 2015; 13(29): 7911 doi: 10.1039/C5OB01051A
75
Yili Shen, Haijian Cai, Shenjie Ma, Wenjing Zhu, Haiyang Zhao, Jifa Li, Hua Ye, Lehe Yang, Chengguang Zhao, Xiaoying Huang, Zhongxiao Xiao. Telocinobufagin Has Antitumor Effects in Non-Small-Cell Lung Cancer by Inhibiting STAT3 SignalingJournal of Natural Products 2022; 85(4): 765 doi: 10.1021/acs.jnatprod.1c00761
76
LIN YE, YONGNING JIA, KE JI, ANDREW J. SANDERS, KAN XUE, JIAFU JI, MALCOLM D. MASON, WEN G. JIANG. Traditional Chinese medicine in the prevention and treatment of cancer and cancer metastasisOncology Letters 2015; 10(3): 1240 doi: 10.3892/ol.2015.3459
77
Wentao Jia, Jiaying Yuan, Binbin Cheng, Changquan Ling. Targeting tumor-derived exosome-mediated premetastatic niche formation: The metastasis-preventive value of traditional Chinese medicineCancer Letters 2023; 567: 216261 doi: 10.1016/j.canlet.2023.216261
78
Wenpan Peng, Yong Xu, Fanchao Feng, Cheng Gu, Zhichao Wang, Di Han, Xianmei Zhou, Hailang He, Juntra Karbwang. Meta-Analysis of Therapy of Cinobufacini Capsule Adjunct with First-Line Platinum-Based Chemotherapy for the Treatment of Advanced NSCLCEvidence-Based Complementary and Alternative Medicine 2021; 2021: 1 doi: 10.1155/2021/5596415
79
Fanghua Qi, Anyuan Li, Yoshinori Inagaki, Huanli Xu, Dongliang Wang, Xiaoyan Cui, Li Zhang, Norihiro Kokudo, Guanhua Du, Wei Tang. Induction of apoptosis by cinobufacini preparation through mitochondria- and Fas-mediated caspase-dependent pathways in human hepatocellular carcinoma cellsFood and Chemical Toxicology 2012; 50(2): 295 doi: 10.1016/j.fct.2011.10.040
80
Fang Li, Yan Weng, Lihui Wang, Haibing He, Jingyu Yang, Xing Tang. The efficacy and safety of bufadienolides-loaded nanostructured lipid carriersInternational Journal of Pharmaceutics 2010; 393(1-2): 204 doi: 10.1016/j.ijpharm.2010.04.005
81
Ailin Yang, Qi Wu, Qimei Chen, Jingyi Yang, Haoran Li, Yufan Tao, Anmei Wang, Yaxue Sun, Jiayu Zhang. Cinobufagin restrains the growth and triggers DNA damage of human hepatocellular carcinoma cells via proteasome-dependent degradation of thymidylate synthaseChemico-Biological Interactions 2022; 360: 109938 doi: 10.1016/j.cbi.2022.109938
82
Bufalin Induces Apoptosis of MDA-MB-231 Cell Through Activation of JNK/p53 PathwayJournal of Cancer Research Updates 2015; 4(2) doi: 10.6000/1929-2279.2015.04.02.1
83
Xu Wu, Haiyu Zhao, Hongjie Wang, Bo Gao, Jian Yang, Nan Si, Baolin Bian. Simultaneous determination of eight bufadienolides in cinobufacini injection by HPLC coupled with triple quadrupole mass spectrometryJournal of Separation Science 2012; 35(15): 1893 doi: 10.1002/jssc.201200036
84
Tianming Gao, Hua Tang, Baohuan Zhou, Dousheng Bai, Shengjie Jin, Chi Zhang, Guoqing Jiang. Can patients with gallbladder adenocarcinoma and liver metastases obtain survival benefit from surgery? A population-based studyUpdates in Surgery 2022; 74(4): 1353 doi: 10.1007/s13304-022-01302-9
85
Chuan-Ming Xie, Wood Yee Chan, Sidney Yu, Jun Zhao, Christopher H.K. Cheng. Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activationFree Radical Biology and Medicine 2011; 51(7): 1365 doi: 10.1016/j.freeradbiomed.2011.06.016
86
Yingbo Zhang, Xiaomin Tang, Yuxin Pang, Luqi Huang, Dan Wang, Chao Yuan, Xuan Hu, Liping Qu. The Potential Mechanism of Bufadienolide-Like Chemicals on Breast Cancer via Bioinformatics AnalysisCancers 2019; 11(1): 91 doi: 10.3390/cancers11010091
87
Zhaohui Zhu, Hanlu Wang, Xu Qian, Meiling Xue, Aijun Sun, Yifei Yin, Jinhai Tang, Jian Zhang. Inhibitory Impact Of Cinobufagin In Triple-Negative Breast Cancer Metastasis: Involvements Of Macrophage Reprogramming Through Upregulated MME and Inactivated FAK/STAT3 SignalingClinical Breast Cancer 2024;  doi: 10.1016/j.clbc.2024.01.014
88
Shin-Hwar Wu, Yung-Ting Hsiao, Chao-Lin Kuo, Fu-Shun Yu, Shu-Chun Hsu, Ping-Ping Wu, Jaw-Chyun Chen, Te-Chun Hsia, Hsin-Chung Liu, Wu-Huei Hsu, Jing-Gung Chung. Bufalin Inhibits NCI-H460 Human Lung Cancer Cell MetastasisIn Vitroby Inhibiting MAPKs, MMPs, and NF-κB PathwaysThe American Journal of Chinese Medicine 2015; 43(06): 1247 doi: 10.1142/S0192415X15500718
89
Lívia Queiroz de Sousa, Kátia da Conceição Machado, Samara Ferreira de Carvalho Oliveira, Lidiane da Silva Araújo, Evaldo dos Santos Monção-Filho, Ana Amélia de Carvalho Melo-Cavalcante, Gerardo Magela Vieira-Júnior, Paulo Michel Pinheiro Ferreira. Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibitionToxicon 2017; 127: 63 doi: 10.1016/j.toxicon.2017.01.004
90
Xu Deng, Jiexia Sheng, Hua Liu, Nannan Wang, Cuoji Dai, Zhenguo Wang, Jing Zhang, Jianye Zhao, Erqing Dai. Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth <i>via</i> the p73 Signalling PathwayBiological and Pharmaceutical Bulletin 2019; 42(9): 1500 doi: 10.1248/bpb.b19-00174
91
Ning Tang, Lei Shi, Zhenlong Yu, Peipei Dong, Chao Wang, Xiaokui Huo, Baojing Zhang, Shanshan Huang, Sa Deng, Kexin Liu, Tonghui Ma, Xiaobo Wang, Lijun Wu, Xiao-Chi Ma. Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathwayOncotarget 2016; 7(3): 3533 doi: 10.18632/oncotarget.6514
92
Xia Liu, Xiang-yang Xiao, Qi-yang Shou, Jun-feng Yan, Long Chen, Hui-ying Fu, Jian-chao Wang. Bufalin inhibits pancreatic cancer by inducing cell cycle arrest via the c-Myc/NF-κB pathwayJournal of Ethnopharmacology 2016; 193: 538 doi: 10.1016/j.jep.2016.09.047
93
Mohammad Taghizadieh, Motahareh Seyedi, Sara Azhdari, Fatemeh Dashti, Sayad Mohammad Ali Mirazimi, Hossein Bannazadeh Baghi, Javid Sadri Nahand, Michael Aschner, Hamed Mirzaei. Gallbladder Cancer2023; : 3 doi: 10.1007/978-981-19-6442-8_1
94
Paulus S. Wang, Jiun-Yih Yeh, Ching-Han Yu, Shyi-Wu Wang. Evidence-based Anticancer Materia MedicaEvidence-based Anticancer Complementary and Alternative Medicine 2011; : 389 doi: 10.1007/978-94-007-0526-5_18
95
CHUNJIAO LIU, QINHONG KONG, FENG PAN, SHAN JIANG, LINGJIE MENG, GAI HUANG, LIDAN LU, SANHUA LI, YUN LIU. Hellebrigenin induces apoptosis in colorectal cancer Cells through induction of excessive reactive oxygen speciesBIOCELL 2021; 45(4): 943 doi: 10.32604/biocell.2021.015836
96
Zhen Yang, Yang Teng, Hao Wang, Huimin Hou. Enhancement of skin permeation of bufalin by limonene via reservoir type transdermal patch: Formulation design and biopharmaceutical evaluationInternational Journal of Pharmaceutics 2013; 447(1-2): 231 doi: 10.1016/j.ijpharm.2013.02.048