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World J Meta-Anal. Aug 28, 2020; 8(4): 285-291
Published online Aug 28, 2020. doi: 10.13105/wjma.v8.i4.285
Primary small cell neuroendocrine carcinoma of the right posterior tongue
Yu Zhou, Hang-Cheng Zhou, Hui Peng, Zhi-Hong Zhang
Yu Zhou, Hui Peng, Zhi-Hong Zhang, Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China
Hang-Cheng Zhou, Department of Pathology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui Province, China
Author contributions: Zhou Y performed the majority of the writing and prepared the figures and tables; Zhou H-C provided pathological technical support; Peng H performed the writing, review and editing of the manuscript; Zhang Z-H designed the outline and coordinated the writing of the paper; all authors have read and approve the final manuscript.
Conflict-of-interest statement: We have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhi-Hong Zhang, MD, Chairman, Chief Doctor, Professor, Surgeon, Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No. 17 Lujiang Road, Hefei 230001, Anhui Province, China. ghoahfoi@sina.com
Received: March 11, 2020
Peer-review started: March 11, 2020
First decision: June 18, 2020
Revised: July 30, 2020
Accepted: August 22, 2020
Article in press: August 22, 2020
Published online: August 28, 2020
Core Tip

Core Tip: Primary extra-pulmonary small cell neuroendocrine carcinoma (SNEC) is extremely rare. There are only 11 primary SNECs occurring in the oral cavity reported in the English literature. This time, we describe a case of primary SNEC of the right posterior tongue in a 46-year-old man. The treatment of this patient is described in detail. The relevant literature of the 11 previously reported patients was reviewed, and the clinical features, histopathological characteristics, differential diagnosis and therapeutic strategies of this rare tumor were analyzed.