Published online Jun 28, 2020. doi: 10.13105/wjma.v8.i3.233
Peer-review started: May 11, 2020
First decision: June 15, 2020
Revised: June 22, 2020
Accepted: June 28, 2020
Article in press: June 28, 2020
Published online: June 28, 2020
Core tip: There are several excellent reviews at the last decade contributed the role of non-coding RNAs in gastrointestinal stromal tumors (GISTs) carcinogenesis. However, until now, most of them focused only on the microRNAs characteristics. Recently there has been a substantial motion in understanding the role of other non-coding RNAs in GIST progress, like the long non-coding RNAs. This review provides an overview of both microRNAs and long non-coding RNAs role in GIST progression, their potential therapeutic use, their ability to predict drug sensitivity and many other aspects concerning GIST development.