Isolated synchronous Virchow lymph node metastasis of sigmoid cancer: A case report

Table 1 Long-term survival of cases with synchronous Virchow lymph node metastasis of colorectal cancer

No.	Ref.	Year	Age/gender	Primary location	Metastasis of another organ	Resection of Virchow LN	Postoperative chemotherapy	Disease free survival time	Overall survival time
1	Watanabe et al[3]	2009	73/Male	Cecum	Paraaortic lymph nodes; Lung	-	5-fluorouracil, Leucovorin, FOLFOX, FOLFIRI	-	3 yr
2	Hirose et al[4]	2010	57/Male	Rectum	-	-	FOLFOX, FOLFIRI	-	3 yr
3	Ando et al[5]	2013	63/Male	Sigmoid colon	-	-	FOLFOX, FOLFIRI	-	5 yr
4	Suliman et al[6]	2019	54/Male	Transverse colon	-	+	FOLFOX, FOLFIRI	-	-
5	Our case	2020	56/Male	Sigmoid colon	-	+	FOLFOX, capecitabine, cetuximab	So far	So far

FOLFOX: Fluorouracil, leucovorin and oxaliplatin; FOLFIRI: Fluorouracil, leucovorin and irinotecan; LN: Lymph node.

Table 2 Information from this case report organized into a timeline

Time lane	Events
June 3, 2020	The male presented with a left cervical mass for one month
June 9, 2020	Lymph node biopsy was performed and histopathological examination revealed that the metastatic adenocarcinoma was found in the tissue
June 18, 2020	The patient underwent gastroenteroscopy and the results revealed that one pedunculated polyp with mucosal erosion was observed in sigmoid colon, and histological examination revealed that adenocarcinoma was found in the intramucosal tissue
June 30, 2020 to September 30, 2020	Undergoing 6 cycles of chemotherapy with FOLFOX + cetuximab regimen
October 22, 2020	The resection of sigmoid carcinoma and mesenteric lymph node dissection were performed. Histological examination showed moderately differentiated adenocarcinoma localized in the mucosa, and one of five paracolic lymph nodes contained metastatic carcinoma (ypT1N1M1)
November 30, 2020 to January 30, 2021	Undergoing 4 cycles of chemotherapy with FOLFOX + capecitabine regimen
February 24, 2021	Virchow lymph node dissection was selected by mutual consultation between the patient and us
February 25, 2021 to March 5, 2021	Postoperative lymphatic leakage
March 24, 2021-So far	The patient received chemotherapy with capecitabine and cetuximab. At nearly half of a year following the surgery, the patient was asymptomatic, and there were no signs of tumor recurrence or progression

FOLFOX: Fluorouracil, leucovorin and oxaliplatin.