Successful treatment of Purpureocillium lilacinum pulmonary infection with isavuconazole: A case report

Figure 1 Chest computed tomography on admission and post-treatment. A: Pulmonary consolidation in the posterior segment of the right lower lobe at admission [axial thorax computed tomography (CT) view); B: Mass consolidation in the posterior segment of the right lower lobe at admission (coronal thorax CT view); C: Lesion reduction in pulmonary consolidation in the posterior segment of the right lower lobe after 2 wk of isavuconazole treatment (axial thorax CT view); D: Lesion reduction in pulmonary consolidation in the posterior segment of the right lower lobe after 2 wk of isavuconazole treatment (coronal thorax CT view); E: Significant absorption of pulmonary consolidation in the posterior segment of the right lower lobe at 6 wk of discharge (axial thorax CT view); F: Significant absorption of pulmonary consolidation in the posterior segment of the right lower lobe at 6 wk of discharge (coronal thorax CT view).

Figure 2 Culture and microscopic examination of the microorganisms. A: Salmonella glucose agar, 28 °C, culture for 7 d, the purplish colony were concentric on the front; B: Yellowish-pale colonies on the back; C: Colorless hyaline branching filaments were observed under light microscopy, and the spores were erect, with a broomy tip and a cone-shaped, fine bony tip at the base of the flask. The spores were mainly oval or near-spherical in shape, and the chains were cylindrical or discrete.