Unusual presentation of penile giant condyloma acuminatum with spontaneous prepuce perforation: A case report

Figure 1 Images of physical examination. A: An ulcerative hole (indicated by a orange arrow) measuring 1 cm in diameter, with pus discharge, was located under the base of the prepuce; B: Multiple condyloma lesions were present over the exogenitalia, penile shaft, pubis, and groin region, appearing as cauliflower-like warts and plaques.

Figure 2 The circumcised redundant prepuce. A: The circumcised redundant prepuce was measured 7.5 cm × 4.7 cm × 3.1 cm in size; B: The circumcised redundant prepuce showed multiple papillary tumors and microscopic condyloma acuminata with moderate dysplasia (hematoxylin and eosin staining, × 20).

Figure 3 This is a follow-up photo six months after surgery. Considering the patient’s advanced age, we used adjuvant topical imiquimod and oral chemotherapy medication tegafur-uracil, and the control was good, with no new local recurrence of condyloma acuminatum.